Effect of elexacaftor/tezacaftor/ivacaftor on mucus and mucociliary clearance in cystic fibrosis
Background The cystic fibrosis transmembrane conductance regulator (CFTR) modulator
elexacaftor/tezacaftor/ivacaftor (E/T/I) is highly effective clinically for those with at least one …
elexacaftor/tezacaftor/ivacaftor (E/T/I) is highly effective clinically for those with at least one …
Water Sorption and Structural Properties of Human Airway Mucus in Health and Muco-Obstructive Diseases
Muco-obstructive diseases change airway mucus properties, impairing mucociliary transport
and increasing the likelihood of infections. To investigate the sorption properties and …
and increasing the likelihood of infections. To investigate the sorption properties and …
Ex-vivo effects of intrapulmonary percussive ventilation on sputum rheological properties
N Wiame, MR de Saint-Vincent, N Audag… - Respiratory physiology …, 2023 - Elsevier
Intrapulmonary percussive ventilation (IPV) has been postulated to enhance mucociliary
clearance by improving tracheobronchial sputum rheological properties. The IPV effects on …
clearance by improving tracheobronchial sputum rheological properties. The IPV effects on …
Temporal changes over time in sputum rheological parameters after SARS-CoV-2 infection in two patients with chronic cough
H Ogawa, Y Uchida - Respiratory Investigation, 2024 - Elsevier
We report temporal changes in sputum rheological parameters after SARS-CoV-2 infection
in two patients with chronic cough (71-year-old, male, sinobronchial syndrome; 80-year-old …
in two patients with chronic cough (71-year-old, male, sinobronchial syndrome; 80-year-old …
The intermittent intrapulmonary deflation technique for airway clearance in patients with cystic fibrosis: A randomized trial
JRFF de Macedo, AS Aubriot, G Reychler… - … Medicine and Research, 2024 - Elsevier
Background Cystic fibrosis (CF) is a muco-obstructive lung disease characterized by thick
sputum with abnormal rheological properties. The intermittent intrapulmonary deflation (IID) …
sputum with abnormal rheological properties. The intermittent intrapulmonary deflation (IID) …