Critical review of biodegradable and bioactive polymer composites for bone tissue engineering and drug delivery applications

S Sharma, P Sudhakara, J Singh, RA Ilyas… - Polymers, 2021 - mdpi.com
In the determination of the bioavailability of drugs administered orally, the drugs' solubility
and permeability play a crucial role. For absorption of drug molecules and production of a …

Sol-gel processing of bioactive glass nanoparticles: A review

K Zheng, AR Boccaccini - Advances in Colloid and Interface Science, 2017 - Elsevier
Silicate-based bioactive glass nanoparticles (BGN) are gaining increasing attention in
various biomedical applications due to their unique properties. Controlled synthesis of BGN …

[HTML][HTML] Multi-functional silica-based mesoporous materials for simultaneous delivery of biologically active ions and therapeutic biomolecules

H Zhu, K Zheng, AR Boccaccini - Acta Biomaterialia, 2021 - Elsevier
Mesoporous silica-based materials, especially mesoporous bioactive glasses (MBGs), are
being highly considered for biomedical applications, including drug delivery and tissue …

[HTML][HTML] Mesoporous bioactive glasses for regenerative medicine

M Vallet-Regi, AJ Salinas - Materials Today Bio, 2021 - Elsevier
Stem cells are the central element of regenerative medicine (RM). However, in many clinical
applications, the use of scaffolds fabricated with biomaterials is required. In this sense …

Metal ions: The unfading stars of bone regeneration—From bone metabolism regulation to biomaterial applications

Y Luo, H Liu, Y Zhang, Y Liu, S Liu, X Liu… - Biomaterials Science, 2023 - pubs.rsc.org
In recent years, bone regeneration has emerged as a remarkable field that offers promising
guidance for treating bone-related diseases, such as bone defects, bone infections, and …

[HTML][HTML] Preparation of 5-fluorouracil-loaded chitosan nanoparticles and study of the sustained release in vitro and in vivo

L Sun, Y Chen, Y Zhou, D Guo, Y Fan, F Guo… - Asian journal of …, 2017 - Elsevier
The sustained-release properties of the biodegradable nano-drug delivery systems were
used to improve the residence time of the chemotherapeutic agent in the body. These drug …

Bone diseases: Current approach and future perspectives in drug delivery systems for bone targeted therapeutics

G Chindamo, S Sapino, E Peira, D Chirio… - Nanomaterials, 2020 - mdpi.com
Bone diseases include a wide group of skeletal-related disorders that cause mobility
limitations and mortality. In some cases, eg, in osteosarcoma (OS) and metastatic bone …

In vitro osteogenesis by intracellular uptake of strontium containing bioactive glass nanoparticles

P Naruphontjirakul, AE Porter, JR Jones - Acta Biomaterialia, 2018 - Elsevier
Monodispersed strontium containing bioactive glass nanoparticles (Sr-BGNPs) with two
compositions were synthesised, through a modified sol-gel Stöber process, wherein silica …

Biological roles and delivery strategies for ions to promote osteogenic induction

E Bosch-Rué, L Diez-Tercero… - Frontiers in cell and …, 2021 - frontiersin.org
Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic
capability to regenerate upon injury, several pathologies and injuries could hamper the …

A review of multi-functional ceramic nanoparticles in 3D printed bone tissue engineering

N Wang, ST Dheen, JYH Fuh, AS Kumar - Bioprinting, 2021 - Elsevier
The complex and hierarchical structure with high vascularization of human bone limits the
applications of traditional bone tissue engineering, especially in large bone defects …