The term vascular cognitive impairment (VCI) was introduced around the start of the new
millennium and refers to the contribution of vascular pathology to any severity of cognitive …

AIMS: To provide 12-month prevalence and disability burden estimates of a broad range of
mental and neurological disorders in the European Union (EU) and to compare these …

There is an urgent need to develop molecular biomarkers of brain age in order to advance
our understanding of age related neurodegeneration. Recently, we developed a highly …

More than 25 million people in the world today are affected by dementia, most suffering from
Alzheimer's disease. In both developed and developing nations, Alzheimer's disease has …

Background Alzheimer disease (AD) patients are at risk of nutritional insufficiencies because
of physiological and psychological factors. Nutritional compounds are postulated to play a …

Objective: To compare the incidence rates for AD among elderly African-American,
Caribbean Hispanic, and white individuals and to determine whether coincident …

Gene expression profiles were assessed in the hippocampus, entorhinal cortex, superior-
frontal gyrus, and postcentral gyrus across the lifespan of 55 cognitively intact individuals …

Alzheimer disease accounts for 60% to 70% of cases of progressive cognitive impairment in
elderly patients. The total prevalence of AD in the United States is estimated at 2.3 million …

Backgrounds. The production of free radicals has a role in the regulation of biological
function, cellular damage, and the pathogenesis of central nervous system conditions …

Health trends in the fastest growing sector of the population, the oldest old, have received
much attention during the past decade because of the rising costs of medical and long-term …