Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …

Butyrate, a main product of gut microbial fermentation, has been recognized as an important
mediator of gut microbiota regulation in whole body energy homeostasis. However, the …

Microbial-derived short-chain fatty acids (SCFA) acetate, propionate and butyrate may
provide a link between gut microbiota and whole-body insulin sensitivity (IS). In this cross …

Objective Antibiotics change the composition of the intestinal microbiota. The magnitude of
the effect of antibiotics on the microbiota and whether the effects are short-term or persist …

Background Chronic illnesses like obesity, type 2 diabetes (T2D) and cardiovascular
diseases, are worldwide major causes of morbidity and mortality. These pathological …

In type 2 diabetes, hyperglycemia, insulin resistance, increased inflammation, and oxidative
stress were shown to be associated with the progressive deterioration of beta‐cell function …

Diet has been shown to be a major factor in modulating the structure of the mammalian gut
microbiota by providing specific nutrient sources and inducing environmental changes (pH …

Fatty acids are good energy sources (9 kcal per gram) that aerobic tissues can use except
for the brain (glucose is an alternative source). Apart from the energy source, fatty acids are …

Metabolic syndrome (MetS) and the associated incidence of cardiovascular disease and
type 2 diabetes represents a significant contributor to morbidity and mortality worldwide …