Blood‐based biomarkers and traumatic brain injury—A clinical perspective

JP Posti, O Tenovuo - Acta Neurologica Scandinavica, 2022 - Wiley Online Library
Blood‐based biomarkers are promising tools to complement clinical variables and imaging
findings in the diagnosis, monitoring and outcome prediction of traumatic brain injury (TBI) …

[HTML][HTML] Systemic immune response in young and elderly patients after traumatic brain injury

M Magatti, F Pischiutta, F Ortolano, A Pasotti… - Immunity & …, 2023 - Springer
Background Traumatic brain injury (TBI) is a leading cause of death and long-term disability
worldwide. In addition to primary brain damage, systemic immune alterations occur, with …

Inflammation biomarkers IL‑6 and IL‑10 may improve the diagnostic and prognostic accuracy of currently authorized traumatic brain injury tools

C Tsitsipanis, M Miliaraki, E Paflioti… - Experimental and …, 2023 - spandidos-publications.com
Traumatic brain injury (TBI) is currently one of the leading causes of mortality and disability
worldwide. At present, no reliable inflammatory or specific molecular neurobiomarker exists …

Outlier analysis for acute blood biomarkers of moderate and severe traumatic brain injury

O Korhonen, M Mononen, M Mohammadian… - Journal of …, 2024 - liebertpub.com
Blood biomarkers have been studied to improve the clinical assessment and prognostication
of patients with moderate-severe traumatic brain injury (mo/sTBI). To assess their clinical …

[HTML][HTML] Plasma Neurofilament Light Chain (NF-L) is a prognostic biomarker for cortical damage evolution but not for cognitive impairment or Epileptogenesis following …

M Heiskanen, O Jääskeläinen, E Manninen… - International Journal of …, 2022 - mdpi.com
Plasma neurofilament light chain (NF-L) levels were assessed as a diagnostic biomarker for
traumatic brain injury (TBI) and as a prognostic biomarker for somatomotor recovery …

[HTML][HTML] Comparison of GFAP and UCH-L1 Measurements Using Two Automated Immunoassays (i-STAT® and Alinity®) for the Management of Patients with Mild …

C Oris, C Khatib-Chahidi, B Pereira… - International Journal of …, 2024 - mdpi.com
The measurement of blood glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-
terminal hydrolase L1 (UCH-L1) may assist in the management of mild traumatic brain injury …

[HTML][HTML] Trajectories of interleukin 10 and heart fatty acid-binding protein levels in traumatic brain injury patients with or without extracranial injuries

TJU Niiranen, AC Chiollaz, RSK Takala… - Frontiers in …, 2023 - frontiersin.org
Background Interleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have gained
interest as diagnostic biomarkers of traumatic brain injury (TBI), but factors affecting their …

Markers of brain injury in patients with aneurysmal subarachnoid hemorrhage

J Fang, J Wang, Y Wang, Y Song - International Journal of …, 2024 - Taylor & Francis
The aim of the study was to investigate the correlation of serum changes and markers of
brain injury (BI) in cerebrospinal fluid (CSF) with postoperative cognitive dysfunction (POCD) …

Determining the value of early measurement of interleukin-10 in predicting the absence of brain lesions in CT scans of patients with mild traumatic brain injury

M Khosh-Fetrat, F Kosha, A Ansari-Moghaddam… - Journal of the …, 2023 - Elsevier
Blood-based biomarkers were recently proposed as predictors of traumatic brain injury (TBI)
outcomes. This would be a critical step forward since the majority of TBI events are mild and …

[HTML][HTML] TBICheck: A Rapid Test to Rule-Out CT scans in Mild Traumatic Brain Injury Patients

L Azurmendi, N Cancelliere, L Sempere… - Medical Research …, 2023 - esmed.org
Abstract Introduction: The TBICheck TM Rapid test is an immunochromatographic rapid test
capable of assisting in the triage of patients with mild Traumatic Brain Injury suspected of …