With regard to the varied, nonculinary uses of hot pepper, there is apparently little new under
the sun. For example, Incas burned dried chili peppers to combat the invading Spaniards by …

Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …

Capsaicin, the pungent ingredient of chilli peppers has become a “hot” topic in neuroscience
with yearly publications over half thousand papers. It is outlined in this survey how this …

Somatostatin is an endogeneous cyclic tetradecapeptide hormone that exerts multiple
biological activities via five ubiquitously distributed receptor subtypes. Classified as a broad …

Capsaicin is a potent agonist of the Transient Receptor Potential Vanilloid type 1 (TRPV1)
channel and is a common component found in the fruits of the genus Capsicum plants …

Capsaicin-sensitive, TRPV1 (transient receptor potential vanilloid 1) receptor-expressing
primary sensory neurons exert local and systemic efferent effects besides the classical …

The present review focuses on promising new opportunities for anti-inflammatory and
analgesic therapy. The theoretical background is an original observation based on our own …

Transient Receptor Potential Ankyrin 1 (TRPA1) channels are localized on sensory nerves
and several non-neural cells, but data on their functional significance are contradictory. We …

Our knowledge of the pathophysiology of affect dysregulation has progressively increased,
but the pharmacological treatments remain inadequate. Here, we summarize the current …

Objective We previously demonstrated that somatostatin (SOM) released from the activated
peripheral terminals of capsaicin‐sensitive primary sensory neurons inhibits acute …