Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Recent transcriptome analyses have revealed that noncoding RNAs (ncRNAs) are broadly
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …

The human genome is pervasively transcribed, producing a majority of short and long
noncoding RNAs (lncRNAs) that can influence cellular programs through a variety of …

Introduction lncRNAs are major players in regulatory networks orchestrating multiple cellular
functions, such as 3D chromosomal interactions, epigenetic modifications, gene expression …

Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders of aging
that impairs predominately dopaminergic neurons. N6-methyladenosine (m6A) is the most …

In late 2012 it was evidenced that most of the human genome is transcribed but only a small
percentage of the transcripts are translated. This observation supported the importance of …

The rapid advance of RNA sequencing technologies contributed to a deep understanding of
transcriptome composition and has allowed the discovery of a large number of non-coding …

The recent discovery of vast non-coding RNA-based regulatory networks that can be easily
modulated by nucleic acid-based drugs has opened numerous new therapeutic possibilities …

Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …