Frailty represents one of the most critical issues facing health care due to its inherent
relationship with poor health care outcomes. Frailty is present in 10% to 20% of individuals …

This paper will update care providers on the clinical and scientific aspects of frailty which
affects an increasing proportion of older people living with HIV (PLWH). The successful use …

Objectives: Aging with HIV is associated with multisystem vulnerability that might be well
characterized by frailty. We sought to construct a frailty index based on health deficit …

The increasing life spans of people infected with human immunodeficiency virus (HIV) reflect
enormous treatment successes and present new challenges related to aging. Even with …

Objectives To describe the prevalence and predictors of frailty in individuals with the human
immunodeficiency virus (HIV) using systematic review methodology. Design Review. Setting …

Modern ART has now achieved the goal of maintaining HIV RNA suppression with minimum
drug-related toxicities. Indeed, in high-income settings, the main health issues in adult …

Although the field of frailty research has expanded rapidly, it is still a nascent concept within
the clinical specialties. Frailty, conceptualized as greater vulnerability to stressors because …

Background. Serum markers of inflammation increase with age and have been strongly
associated with adverse clinical outcomes among both HIV-infected and uninfected adults …

HIV infection, in many circumstances, can now be managed as a chronic disease due to the
marked increase in life expectancy since the introduction of combination antiretroviral …

Therapies targeted at fundamental processes of aging may hold great promise for
enhancing the health of a wide population by delaying or preventing a range of age-related …