Multiple myeloma (MM) is a B cell malignancy resulting in osteolytic lesions and fractures. In
the disease state, bone healing is limited owing to increased osteoclastic and decreased …

Simple Summary This article provides a comprehensive review of new and emerging
treatment strategies against multiple myeloma that employ precision medicines and/or drugs …

CTCF and cohesin play a key role in organizing chromatin into topologically associating
domain (TAD) structures. Disruption of a single CTCF binding site is sufficient to change …

Multiple myeloma (MM) is a common hematologic malignancy for which the underlying
molecular mechanisms remain largely unclear. This study aimed to elucidate key candidate …

Purpose Multiple myeloma (MM) remains an incurable hematologic malignancy which
ultimately develops drug resistance and evades treatment. Despite substantial therapeutic …

PURPOSE: Elevated IL-17 produced by T h 17 cells was reported to promote myeloma cell
growth and inhibit immune function in multiple myeloma (MM). IL-17A was also reported to …

Mapping of quantitative trait loci (QTL) is essential for the discovery of genetic structures that
related to complex quantitative traits. In this study, we identified 264,072 raw SNPs (single …

Multiple Myeloma (MM) is B-cell malignancy characterized by the accumulation and
dissemination of antibody-secreting plasma cells throughout the bone marrow. MM is a …