Genomic profiling for clinical decision making in lymphoid neoplasms
L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …
sequencing technologies, the genomic features of most lymphoid neoplasms have been …
[HTML][HTML] Genetic profiling and biomarkers in peripheral T-cell lymphomas: current role in the diagnostic work-up
Peripheral T-cell lymphomas are a heterogeneous, and usually aggressive, group of mature
T-cell neoplasms with overlapping clinical, morphologic and immunologic features. A large …
T-cell neoplasms with overlapping clinical, morphologic and immunologic features. A large …
A Comparison of the Fifth World Health Organization and the International Consensus Classifications of Mature T-Cell Lymphomas
PP Piccaluga, SS Khattab - International Journal of Molecular Sciences, 2023 - mdpi.com
Peripheral T-cell lymphomas (PTCLs) are a rare subset of non-Hodgkin lymphomas that
often carry significant difficulty in diagnosis and classification because of their rarity and …
often carry significant difficulty in diagnosis and classification because of their rarity and …
Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of non-Hodgkin lymphomas
with poor prognosis. Up to 30% of PTCL lack distinctive features and are classified as PTCL …
with poor prognosis. Up to 30% of PTCL lack distinctive features and are classified as PTCL …
Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness
Y Zhang, X Xiong, R Sun, X Zhu, C Wang… - Journal of Biological …, 2023 - ASBMB
Aberrant overexpression of nonreceptor tyrosine kinase FER (Fps/Fes Related) has been
reported in various ovarian carcinoma–derived tumor cells and is a poor prognosis factor for …
reported in various ovarian carcinoma–derived tumor cells and is a poor prognosis factor for …
Tyrosine kinases in nodal peripheral T-cell lymphomas
PP Piccaluga, C Cascianelli, G Inghirami - Frontiers in Oncology, 2023 - frontiersin.org
Nodal peripheral T-cell lymphomas (PTCL) are uncommon and heterogeneous tumors
characterized by a dismal prognosis. Targeted therapy has been proposed. However …
characterized by a dismal prognosis. Targeted therapy has been proposed. However …
Mature T-cell and NK-cell lymphomas: updates on molecular genetic features
NE Lewis, R Sardana, A Dogan - International Journal of Hematology, 2023 - Springer
Mature T-cell and NK-cell lymphomas are a heterogeneous group of rare and typically
aggressive neoplasms. Diagnosis and subclassification have historically relied primarily on …
aggressive neoplasms. Diagnosis and subclassification have historically relied primarily on …
Pathologic and molecular insights in nodal T-follicular helper cell lymphomas
T-follicular helper (TFH) cells are one of the T-cell subsets with a critical role in the
regulation of germinal center (GC) reactions. TFH cells contribute to the positive selection of …
regulation of germinal center (GC) reactions. TFH cells contribute to the positive selection of …
Pathological and molecular features of nodal peripheral T-cell lymphomas
A Satou, T Takahara, T Tsuzuki - Diagnostics, 2022 - mdpi.com
Peripheral T-cell lymphomas (PTCLs) are uncommon neoplasms derived from mature T
cells or NK cells. PTCLs comprise numerous disease entities, with over 30 distinct entities …
cells or NK cells. PTCLs comprise numerous disease entities, with over 30 distinct entities …
An update on genetic aberrations in T-cell neoplasms
T-cell neoplasms are a highly heterogeneous group of leukaemias and lymphomas that
represent 10–15% of all lymphoid neoplasms. Traditionally, our understanding of T-cell …
represent 10–15% of all lymphoid neoplasms. Traditionally, our understanding of T-cell …