The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …

The use of radiotherapy, either in the form of stereotactic radiosurgery (SRS) or whole-brain
radiotherapy (WBRT), remains the cornerstone for the treatment of brain metastases (BM) …

Glioblastoma is the most common and most aggressive primary brain tumour. Standard of
care consists of surgical resection followed by radiotherapy and concomitant and …

OBJECTIVE: We sought to investigate the concurrence of posterior reversible
encephalopathy syndrome (PRES) with eclampsia and to describe the obstetric …

Object The astrocytic contribution to the blood-brain barrier (BBB) in metastatic and primary
malignant brain tumors is not well understood. To better understand the vascular properties …

Glioblastoma is the most common and uncompromising primary brain tumour and is
characterized by a dismal prognosis despite aggressive treatment regimens. At the cellular …

Glioblastoma (GBM) is inevitably refractory to surgery and chemoradiation. The hope for
immunotherapy has yet to be realised in the treatment of GBM. Immune checkpoint blockade …

Objective Radiation therapy is a cornerstone of brain metastasis (BrM) management but
carries the risk of radiation necrosis (RN), which can require resection for palliation or …

Opinion statement Cranial radiation is ubiquitous in the treatment of primary malignant and
benign brain tumors as well as brain metastases. Improvement in radiotherapy targeting and …

Opinion statement Intracranial stereotactic radiosurgery (SRS) is an effective and convenient
treatment for many brain conditions. Data regarding safety come mostly from retrospective …