The role of the intestinal tract as a reservoir and source for transmission of nosocomial pathogens

CJ Donskey - Clinical infectious diseases, 2004 - academic.oup.com
The intestinal tract provides an important reservoir for many nosocomial pathogens,
including Enterococcus species, Enterobacteriaciae, Clostridium difficile, and Candida …

Antibiotic use and resistance in long term care facilities

LW van Buul, JT van der Steen, RB Veenhuizen… - Journal of the American …, 2012 - Elsevier
INTRODUCTION: The common occurrence of infectious diseases in nursing homes and
residential care facilities may result in substantial antibiotic use, and consequently antibiotic …

Ecological modeling from time-series inference: insight into dynamics and stability of intestinal microbiota

RR Stein, V Bucci, NC Toussaint… - PLoS computational …, 2013 - journals.plos.org
The intestinal microbiota is a microbial ecosystem of crucial importance to human health.
Understanding how the microbiota confers resistance against enteric pathogens and how …

Enterococci facilitate polymicrobial infections

W Xu, Y Fang, K Zhu - Trends in microbiology, 2024 - cell.com
Enterococci are ubiquitous members of the gut microbiota in human beings and animals and
are among the most important nosocomial organisms. Due to their opportunistic …

Infection control measures to limit the spread of Clostridium difficile

RP Vonberg, EJ Kuijper, MH Wilcox… - Clinical Microbiology …, 2008 - Wiley Online Library
Clostridium difficile‐associated diarrhoea (CDAD) presents mainly as a nosocomial
infection, usually after antimicrobial therapy. Many outbreaks have been attributed to C …

Colonisation with ESBL-producing and carbapenemase-producing Enterobacteriaceae, vancomycin-resistant enterococci, and meticillin-resistant Staphylococcus …

C Ludden, M Cormican, A Vellinga, JR Johnson… - BMC infectious …, 2015 - Springer
Background This study examined colonisation with and characteristics of antimicrobial-
resistant organisms among residents of a long-term care facility (LTCF) over one year …

Antianaerobic antibiotic therapy promotes overgrowth of antibiotic-resistant, gram-negative bacilli and vancomycin-resistant enterococci in the stool of colonized …

A Bhalla, NJ Pultz, AJ Ray, CK Hoyen… - Infection Control & …, 2003 - cambridge.org
Background and Objective: Antianaerobic antibiotic therapy promotes persistent high-
density growth of vancomycin-resistant enterococci (VRE) in the stool of colonized patients …

Microbiota-Based Therapies for Clostridium difficile and Antibiotic-Resistant Enteric Infections

BB Lewis, EG Pamer - Annual review of microbiology, 2017 - annualreviews.org
Bacterial pathogens are increasingly antibiotic resistant, and development of clinically
effective antibiotics is lagging. Curing infections increasingly requires antimicrobials that are …

Gastrointestinal colonization with a cephalosporinase-producing bacteroides species preserves colonization resistance against vancomycin-resistant enterococcus …

U Stiefel, MM Nerandzic, MJ Pultz… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Antibiotics that are excreted into the intestinal tract may disrupt the indigenous intestinal
microbiota and promote colonization by health care-associated pathogens. β-Lactam, or …

Occurrence of co-colonization or co-infection with vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus in a medical intensive care unit

DK Warren, A Nitin, C Hill, VJ Fraser… - Infection Control & …, 2004 - cambridge.org
Objective: To determine the occurrence of co-colonization or co-infection with VRE and
MRSA among medical patients requiring intensive care. Design: Prospective, single-center …