Selective drivers of simple multicellularity

K Tong, GO Bozdag, WC Ratcliff - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•We survey ten key selective drivers favouring the evolution of simple
multicellularity.•The selective drivers of multicellularity depend on both lineage and …

[HTML][HTML] Roles of ESCRT-III polymers in cell division across the tree of life

JG Carlton, B Baum - Current opinion in cell biology, 2023 - Elsevier
Every cell becomes two through a carefully orchestrated process of division. Prior to division,
contractile machinery must first be assembled at the cell midzone to ensure that the cut …

Open-endedness in synthetic biology: a route to continual innovation for biological design

M Stock, TE Gorochowski - Science Advances, 2024 - science.org
Design in synthetic biology is typically goal oriented, aiming to repurpose or optimize
existing biological functions, augmenting biology with new-to-nature capabilities, or creating …

Morphological Entanglement in Living Systems

TC Day, SA Zamani-Dahaj, GO Bozdag, AJ Burnetti… - Physical Review X, 2024 - APS
Many organisms exhibit branching morphologies that twist around each other and become
entangled. Entanglement occurs when different objects interlock with each other, creating …

'Evolutionary poker': an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments

RS Root‐Bernstein, MI Bernstein - The Journal of Physiology, 2024 - Wiley Online Library
A simple agent‐based model is presented that produces results matching the experimental
data found by Lenski's group for≤ 50,000 generations of Escherichia coli bacteria under …

Bacteria evolve macroscopic multicellularity by the genetic assimilation of phenotypically plastic cell clustering

Y Chavhan, S Dey, PA Lind - Nature Communications, 2023 - nature.com
The evolutionary transition from unicellularity to multicellularity was a key innovation in the
history of life. Experimental evolution is an important tool to study the formation of …

The shift to 3D growth during embryogenesis of kelp species, atlas of cell division and differentiation of Saccharina latissima

I Theodorou, B Charrier - Development, 2023 - journals.biologists.com
In most organisms, 3D growth takes place at the onset of embryogenesis. In some brown
algae, 3D growth occurs later in development, when the organism consists of several …

Proteostatic tuning underpins the evolution of novel multicellular traits

K Montrose, DT Lac, AJ Burnetti, K Tong… - Science …, 2024 - science.org
The evolution of multicellularity paved the way for the origin of complex life on Earth, but little
is known about the mechanistic basis of early multicellular evolution. Here, we examine the …

[HTML][HTML] Cross-regulations of two connected domains form a mechanical circuit for steady force transmission during clathrin-mediated endocytosis

Y Ren, J Yang, B Fujita, Y Zhang, J Berro - Cell reports, 2024 - cell.com
Mechanical forces are transmitted from the actin cytoskeleton to the membrane during
clathrin-mediated endocytosis (CME) in the fission yeast Schizosaccharomyces pombe …

A year at the forefront of hydrostat motion

AK Schulz, N Schneider, M Zhang, K Singal - Biology Open, 2023 - journals.biologists.com
Currently, in the field of interdisciplinary work in biology, there has been a significant push
by the soft robotic community to understand the motion and maneuverability of hydrostats …