Mechanisms of action and clinical implications of MicroRNAs in the drug resistance of gastric cancer

Y Liu, X Ao, G Ji, Y Zhang, W Yu, J Wang - Frontiers in oncology, 2021 - frontiersin.org
Gastric cancer (GC) is one of the most common malignant tumors of digestive systems
worldwide, with high recurrence and mortality. Chemotherapy is still the standard treatment …

The role of autophagy in gastric cancer chemoresistance: friend or foe?

JL Xu, L Yuan, YC Tang, ZY Xu, HD Xu… - Frontiers in Cell and …, 2020 - frontiersin.org
Gastric cancer is the third most common cause of cancer-related death worldwide. Drug
resistance is the main inevitable and vital factor leading to a low 5-year survival rate for …

Identification of a six‐microRNA signature as a potential diagnostic biomarker in breast cancer tissues

M Mahmoudian, E Razmara… - Journal of clinical …, 2021 - Wiley Online Library
Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …

Notch signaling pathway: a comprehensive prognostic and gene expression profile analysis in breast cancer

H Yousefi, A Bahramy, N Zafari, MR Delavar, K Nguyen… - BMC cancer, 2022 - Springer
Breast cancer is a complex disease exhibiting a great degree of heterogeneity due to
different molecular subtypes. Notch signaling regulates the differentiation of breast epithelial …

Role of non-coding RNAs in colorectal cancer: focus on long non-coding RNAs

M Lulli, C Napoli, I Landini, E Mini… - International journal of …, 2022 - mdpi.com
Simple Summary Non-coding RNAs are a type of RNA that is not translated into proteins.
They play important roles in several cellular processes, mainly in the regulation of genetic …

Mechanisms of long non‐coding RNA function in colorectal cancer tumorigenesis

A Poursheikhani, MR Abbaszadegan… - Asia‐Pacific Journal …, 2021 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common cancers globally. Although a variety of
CRC screening methods have been developed, many patients are diagnosed at advanced …

CircSOD2 polarizes macrophages towards the M1 phenotype to alleviate cisplatin resistance in gastric cancer cells by targeting the miR-1296/STAT1 axis

B Qu, J Liu, Z Peng, Z Xiao, S Li, J Wu, S Li, J Luo - Gene, 2023 - Elsevier
Cisplatin is the first-line drug for gastric cancer (GC). Cisplatin resistance is the most
important cause of poor prognosis for GC. Increasing evidence has identified the important …

Non-coding RNAs in gastric cancer: from malignant hallmarks to clinical applications

D Chen, S Ping, Y Xu, M Wang, X Jiang… - Frontiers in Cell and …, 2021 - frontiersin.org
Gastric cancer (GC) is one of the most lethal malignancies worldwide. However, the
molecular mechanisms underlying gastric carcinogenesis remain largely unknown. Over the …

Contribution of circRNAs in gastric cancer

S Ghafouri-Fard, KH Tamizkar, E Jamali… - … -Research and Practice, 2021 - Elsevier
Gastric cancer (GC) is one of the most commonly diagnosed neoplasms in the world. A
number of environmental and lifestyle factors, particularly chronic infection with Helicobacter …

All-trans retinoic acid-mediated miR-30a up-regulation suppresses autophagy and sensitizes gastric cancer cells to cisplatin

A Abbasi, M Hosseinpourfeizi, R Safaralizadeh - Life Sciences, 2022 - Elsevier
Aims The potential of all-trans retinoic acid (ATRA) in regulating some microRNAs (miRNAs)
involved in multiple cancer-related pathways, including resistance to chemotherapeutics …