The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Considerable progress has been made in understanding the basic mechanisms that
regulate fluid and protein exchange across the endothelial and epithelial barriers of the lung …

Pulmonary alveolar type I (AT1) cells cover more than 95% of alveolar surface and are
essential for the air–blood barrier function of lungs. AT1 cells have been shown to retain …

In 2005, the American Thoracic Society marks its 100th year of existence. For over a third of
this span, since 1967, clinicians and investigators have struggled with a common, often …

The discovery of mechanisms that regulate salt and water transport by the alveolar and
distal airway epithelium of the lung has generated new insights into the regulation of lung …

Rationale: Receptor for advanced glycation end-products (RAGE) is one of the alveolar type
I cell–associated proteins in the lung. Objectives: To test the hypothesis that RAGE is a …

Oral inhalation results in pulmonary drug targeting and thereby reduces systemic side
effects, making it the preferred means of drug delivery for the treatment of respiratory …

Objectives: To determine whether baseline plasma levels of the receptor for advanced
glycation end products (RAGE), a novel marker of alveolar type I cell injury, are associated …

Alveolar type 1 (AT1) cells cover> 95% of the gas exchange surface and are extremely thin
to facilitate passive gas diffusion. The development of these highly specialized cells and its …

The lung surface of air‐breathing vertebrates is formed by a continuous epithelium that is
covered by a fluid layer. In the airways, this epithelium is largely pseudostratified consisting …