Role of ADAM and ADAMTS disintegrin and metalloproteinases in normal pregnancy and preeclampsia
H Qu, RA Khalil - Biochemical Pharmacology, 2022 - Elsevier
Normal pregnancy (NP) involves intricate processes starting with egg fertilization,
proceeding to embryo implantation, placentation and gestation, and culminating in …
proceeding to embryo implantation, placentation and gestation, and culminating in …
The involvement of cell adhesion molecules, tight junctions, and gap junctions in human placentation
EA Adu-Gyamfi, A Czika, PN Gorleku, A Ullah… - Reproductive …, 2021 - Springer
Placentation is a major determinant of the success of pregnancy. It is regulated by several
factors such as cell adhesion molecules, tight junctions, and gap junctions. The cell …
factors such as cell adhesion molecules, tight junctions, and gap junctions. The cell …
Activin A increases human trophoblast invasion by upregulating integrin β1 through ALK4
Activin A promotes human trophoblast invasion during the first trimester of pregnancy and is
associated with preeclampsia and pregnancy‐induced hypertension (PE/PIH) in naturally …
associated with preeclampsia and pregnancy‐induced hypertension (PE/PIH) in naturally …
[HTML][HTML] ADAM8 deficiency in macrophages promotes cardiac repair after myocardial infarction via ANXA2-mTOR-autophagy pathway
Z Ji, J Guo, R Zhang, W Zuo, Y Xu, Y Qu, Z Tao… - Journal of Advanced …, 2024 - Elsevier
Introduction A disintegrin and metalloproteinase 8 (ADAM8), a crucial regulator in
macrophages, is closely associated with cardiovascular disease progression. Objectives …
macrophages, is closely associated with cardiovascular disease progression. Objectives …
Mitochondrial dynamics in placenta-derived mesenchymal stem cells regulate the invasion activity of trophoblast
J Seok, S Jun, JO Lee, GJ Kim - International Journal of Molecular …, 2020 - mdpi.com
Mitochondrial dynamics are involved in many cellular events, including the proliferation,
differentiation, and invasion/migration of normal as well as cancerous cells. Human placenta …
differentiation, and invasion/migration of normal as well as cancerous cells. Human placenta …
ADAM and ADAMTS disintegrin and metalloproteinases as major factors and molecular targets in vascular malfunction and disease
HF Yang, RA Khalil - Advances in Pharmacology, 2022 - Elsevier
Abstract A Disintegrin and Metalloproteinase (ADAM) and A Disintegrin and
Metalloproteinase with Thrombospondin Motifs (ADAMTS) are two closely related families of …
Metalloproteinase with Thrombospondin Motifs (ADAMTS) are two closely related families of …
ADAM8 silencing suppresses the migration and invasion of fibroblast-like synoviocytes via FSCN1/MAPK cascade in osteoarthritis
K Chen, H Tao, P Zhu, M Chu, X Li, Y Shi… - Arthritis Research & …, 2024 - Springer
Objective Osteoarthritis (OA) is a degenerative joint disease that affects elderly populations
worldwide, causing pain and disability. Alteration of the fibroblast-like synoviocytes (FLSs) …
worldwide, causing pain and disability. Alteration of the fibroblast-like synoviocytes (FLSs) …
RETRACTED: Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function
Normal function of placental extravillous trophoblasts (EVTs), which are responsible for
uteroplacental vascular remodeling, is critical for adequate delivery of oxygen and nutrients …
uteroplacental vascular remodeling, is critical for adequate delivery of oxygen and nutrients …
An Extracellular/Membrane-Bound S100P Pool Regulates Motility and Invasion of Human Extravillous Trophoblast Lines and Primary Cells
Whilst S100P has been shown to be a marker for carcinogenesis, we have shown, in non-
physio-pathological states, that its expression promotes trophoblast motility and invasion but …
physio-pathological states, that its expression promotes trophoblast motility and invasion but …
Downregulation of lncRNA IGF2-AS-encoded peptide induces trophoblast–cycle arrest
AH Wu, XL Chen, LY Guo, DF Lu, S Lu… - Reproductive …, 2021 - Elsevier
Abstract Research question lncRNA IGF2-AS may be related to early pregnancy loss. Does
lncRNA IGF2-AS affect trophoblast cell growth? The aim of the present study was to verify …
lncRNA IGF2-AS affect trophoblast cell growth? The aim of the present study was to verify …