[HTML][HTML] Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome
M Zoulikha, Q Xiao, GF Boafo, MA Sallam… - … Pharmaceutica Sinica B, 2022 - Elsevier
The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …
several unmet medical needs, including acute lung injury/acute respiratory distress …
A comprehensive review on the emerging role of long non-coding RNAs in the regulation of NF-κB signaling in inflammatory lung diseases
Public health globally faces significant risks from conditions like acute respiratory distress
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …
Anti‐inflammatory and anticancer activities of Naringenin‐loaded liquid crystalline nanoparticles in vitro
In this study, we had developed Naringenin‐loaded liquid crystalline nanoparticles (LCNs)
and investigated the anti‐inflammatory and anticancer activities of Naringenin‐LCNs against …
and investigated the anti‐inflammatory and anticancer activities of Naringenin‐LCNs against …
[HTML][HTML] Design of functional nanoparticles by microfluidic platforms as advanced drug delivery systems for cancer therapy
Nanoparticle systems are functional carriers that can be used in the cancer therapy field for
the delivery of a variety of hydrophobic and/or hydrophilic drugs. Recently, the advent of …
the delivery of a variety of hydrophobic and/or hydrophilic drugs. Recently, the advent of …
Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
[HTML][HTML] Prospects for RNAi therapy of COVID-19
H Uludağ, K Parent, HM Aliabadi… - … in Bioengineering and …, 2020 - frontiersin.org
COVID-19 caused by the SARS-CoV-2 virus is a fast emerging disease with deadly
consequences. The pulmonary system and lungs in particular are most prone to damage …
consequences. The pulmonary system and lungs in particular are most prone to damage …
Probing the links: Long non-coding RNAs and NF-κB signalling in atherosclerosis
Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …
[HTML][HTML] Macrophage metabolic reprogramming during chronic lung disease
Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …
RNAi-based drug design: considerations and future directions
Q Tang, A Khvorova - Nature Reviews Drug Discovery, 2024 - nature.com
More than 25 years after its discovery, the post-transcriptional gene regulation mechanism
termed RNAi is now transforming pharmaceutical development, proved by the recent FDA …
termed RNAi is now transforming pharmaceutical development, proved by the recent FDA …
Antiproliferative effects of boswellic acid-loaded chitosan nanoparticles on human lung cancer cell line A549
N Solanki, M Mehta, DK Chellappan… - Future medicinal …, 2020 - Future Science
Aim: In the present study boswellic acids-loaded chitosan nanoparticles were synthesized
using ionic gelation technique. The influence of independent variables were studied and …
using ionic gelation technique. The influence of independent variables were studied and …