Familial hypercholesterolaemia is the most commonly encountered genetic condition that
predisposes individuals to premature cardiovascular disease. Nevertheless, most patients …

Surveys and registries are needed to verify that real-life daily practice is in keeping with what
is recommended in the guidelines, thus completing the loop between clinical research …

Background Familial hypercholesterolaemia is a common autosomal-dominant disorder
caused by mutations in three known genes. DNA-based cascade testing is recommended by …

Aims Homozygous autosomal dominant hypercholesterolaemia (hoADH), an orphan
disease caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B …

As atherosclerosis begins in childhood, early diagnosis and treatment of familial
hypercholesterolemia (FH) is considered necessary. The basic diagnosis of pediatric FH …

Cardiovascular disease (CVD) due to atherosclerosis of the arterial vessel wall and to
thrombosis is the foremost cause of premature mortality and of disability-adjusted life years …

Familial hypercholesterolemia (FH) is an autosomal hereditary disease with the 3 major
clinical features of 1) hyper-LDL-cholesterolemia, 2) premature CAD and 3) tendon and skin …

Background: Familial hypercholesterolemia (FH) is the most common genetic disorder
associated with premature atherosclerotic cardiovascular disease (ASCVD). There are …

Familial hypercholesterolaemia is a common inherited disorder characterized by abnormally
elevated serum levels of low-density lipoprotein (LDL) cholesterol from birth, which in time …

Familial hypercholesterolaemia (FH) is an autosomal dominant genetic disorder, associated
with elevated levels of low-density lipoprotein-cholesterol (LDL-C), which can lead to …