Fusarium: a treasure trove of bioactive secondary metabolites

M Li, R Yu, X Bai, H Wang, H Zhang - Natural product reports, 2020 - pubs.rsc.org
Covering up to December 2019 Fusarium, one of the most common fungal genera, has
received considerable attention because of its biosynthetic exuberance, the result of many …

Sesterterpenoids: chemistry, biology, and biosynthesis

K Li, KR Gustafson - Natural Product Reports, 2021 - pubs.rsc.org
Covering: July 2012 to December 2019 Over the last seven years, expanding research
efforts focused on sesterterpenoids has led to the isolation, identification, and …

Aspergillus Carneus metabolite Averufanin induced cell cycle arrest and apoptotic cell death on cancer cell lines via inducing DNA damage

D Demirel, FC Ozkaya, W Ebrahim, E Sokullu… - Scientific Reports, 2023 - nature.com
Cancer is one of the leading causes of death worldwide, accounting for nearly 10 million
deaths in 2020. Current treatment methods include hormone therapy, γ-radiation …

Research progress on fungal sesterterpenoids biosynthesis

P Zhang, J Qi, Y Duan, J Gao, C Liu - Journal of Fungi, 2022 - mdpi.com
Sesterterpenes are 25-carbon terpenoids formed by the cyclization of dimethyl allyl
diphosphate (DMAPP) and isopentenyl diphosphate (IPP) as structural units by …

Anti-multidrug-resistant Staphylococcus aureus and anti-dermatophyte activities of secondary metabolites of the endophytic fungus Penicillium brevicompactum ANT13 …

N Sadrati, A Zerroug, R Demirel, D Harzallah - Archives of Microbiology, 2023 - Springer
This study aims to identify and assess the antimicrobial activity of endophytic fungi found in
the endemic plant Abies numidica. Among all isolates, the ANT13 isolate demonstrated …

[HTML][HTML] Fungi-Derived Bioactive Compounds as Potential Therapeutic Agents for Pancreatic Cancer: A Systematic Review

F Quiñonero, A Ortigosa-Palomo, R Ortiz, C Melguizo… - Microorganisms, 2024 - mdpi.com
Pancreatic cancer (PC) is one of the tumors with the lowest 5-year survival rate worldwide
due to late diagnosis and lack of effective therapy. Because of this, it is necessary to …

Sesterterpenes and macrolide derivatives from the endophytic fungus Aplosporella javeedii

Y Gao, F Stuhldreier, L Schmitt, S Wesselborg, L Wang… - Fitoterapia, 2020 - Elsevier
Abstract Five sesterterpenes (1–5) including two new compounds (1 and 2), as well as a
new (6) and a known macrolide (7) were isolated from the endophytic fungus Aplosporella …

Cytotoxic activity of cholesterol oxidase produced by Streptomyces sp. AKHSS against cancerous cell lines: mechanism of action in HeLa cells

K Alapati, SS Handanahal - World Journal of Microbiology and …, 2021 - Springer
Re-occurrence of cancer is the major drawback for the currently available anticancer
therapies. Therefore, study of an efficient enzyme, cholesterol oxidase produced by various …

Identification and Functional Characterization of the Gene Cluster Responsible for Fusaproliferin Biosynthesis in Fusarium proliferatum

A Ćeranić, T Svoboda, F Berthiller, M Sulyok… - Toxins, 2021 - mdpi.com
The emerging mycotoxin fusaproliferin is produced by Fusarium proliferatum and other
related Fusarium species. Several fungi from other taxonomic groups were also reported to …

Physicochemical, Pharmacokinetic and Cytotoxicity of the Compounds Isolated from an Endophyte Fusarium oxysporum: In Vitro and In Silico Approaches

N Hoque, F Afroz, F Khatun, SR Rony, CM Hasan… - Toxins, 2022 - mdpi.com
The present study was intended to characterize the secondary metabolites of the endophyte
Fusarium oxysporum isolated from the plant Aglaonema hookerianum Schott. And to …