Haematological malignancies were previously thought to be driven solely by genetic or
epigenetic lesions within haematopoietic cells. However, the niches that maintain and …

Cancer is a leading cause of death worldwide and cancer incidence and mortality are
rapidly growing. These massive amounts of cancer patients require rapid diagnosis and …

The historical lack of preclinical models reflecting the genetic heterogeneity of multiple
myeloma (MM) hampers the advance of therapeutic discoveries. To circumvent this …

The development and effectiveness of novel therapies in multiple myeloma have been
established in large clinical trials. However, multiple myeloma remains an incurable …

Multiple myeloma is a clonal disease of long-lived plasma cells and is the second most
common hematological cancer behind Non-Hodgkin's Lymphoma. Malignant transformation …

Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

The TEMPI syndrome is a rare and acquired disorder characterized by 5 salient features,
which compose its name:(1) telangiectasias;(2) elevated erythropoietin and …

In this review article, we present recent updates on the hematologic tumor microenvironment
following the 3 rd Scientific Workshop on the Haematological Tumour Microenvironment and …

Receptor tyrosine kinases (RTKs) are key cell surface receptors involved in cell
communication and signal transduction, with great importance in cell growth, differentiation …

More recently, microbiota was detected in several tumorous tissues including multiple
myeloma (MM), but the roles of which is still under-studied as paucity of research on tumor …