Bio-based production of chemicals, materials and fuels–Corynebacterium glutamicum as versatile cell factory

J Becker, C Wittmann - Current opinion in biotechnology, 2012 - Elsevier
Since their discovery almost 60 years ago, Corynebacterium glutamicum and related
subspecies are writing a remarkable success story in industrial biotechnology. Today, these …

Metabolic engineering of Corynebacterium glutamicum for fermentative production of chemicals in biorefinery

KA Baritugo, HT Kim, Y David, J Choi, SH Hong… - Applied microbiology …, 2018 - Springer
Bio-based production of industrially important chemicals provides an eco-friendly alternative
to current petrochemical-based processes. Because of the limited supply of fossil fuel …

Improvement of the Redox Balance Increases l-Valine Production by Corynebacterium glutamicum under Oxygen Deprivation Conditions

S Hasegawa, K Uematsu, Y Natsuma… - Applied and …, 2012 - Am Soc Microbiol
Production of l-valine under oxygen deprivation conditions by Corynebacterium glutamicum
lacking the lactate dehydrogenase gene ldhA and overexpressing the l-valine biosynthesis …

Engineering of Corynebacterium glutamicum for High-Yield l-Valine Production under Oxygen Deprivation Conditions

S Hasegawa, M Suda, K Uematsu… - Applied and …, 2013 - Am Soc Microbiol
We previously demonstrated efficient l-valine production by metabolically engineered
Corynebacterium glutamicum under oxygen deprivation. To achieve the high productivity, a …

Sigma factors and promoters in Corynebacterium glutamicum

M Pátek, J Nešvera - Journal of biotechnology, 2011 - Elsevier
The Corynebacterium glutamicum genome codes for 7 sigma subunits (factors) of RNA
polymerase (RNAP): primary sigma factor SigA (σA), primary-like SigB and 5 other …

Strain optimization for efficient isobutanol production using Corynebacterium glutamicum under oxygen deprivation

S Yamamoto, M Suda, S Niimi, M Inui… - Biotechnology and …, 2013 - Wiley Online Library
Microbial production of isobutanol is made difficult by the chemical's high cell toxicity.
Corynebacterium glutamicum, inherently one of the more isobutanol‐tolerant industrial …

Corynebacterium glutamicum for Sustainable Bioproduction: From Metabolic Physiology to Systems Metabolic Engineering

J Becker, G Gießelmann, SL Hoffmann… - Synthetic biology …, 2018 - Springer
Since its discovery 60 years ago, Corynebacterium glutamicum has evolved into a
workhorse for industrial biotechnology. Traditionally well known for its remarkable capacity …

Engineering of sugar metabolism of Corynebacterium glutamicum for production of amino acid l-alanine under oxygen deprivation

T Jojima, M Fujii, E Mori, M Inui, H Yukawa - Applied microbiology and …, 2010 - Springer
Corynebacterium glutamicum was genetically engineered to produce l-alanine from sugar
under oxygen deprivation. The genes associated with production of organic acids in C …

Xylitol production by recombinant Corynebacterium glutamicum under oxygen deprivation

M Sasaki, T Jojima, M Inui, H Yukawa - Applied microbiology and …, 2010 - Springer
Wild-type Corynebacterium glutamicum produced 0.6 gl− 1 xylitol from xylose at a
productivity of 0.01 gl− 1 h− 1 under oxygen deprivation. To increase this productivity, the …

Improvement of succinate production by release of end-product inhibition in Corynebacterium glutamicum

SC Chung, JS Park, J Yun, JH Park - Metabolic engineering, 2017 - Elsevier
Succinate is a renewable-based platform chemical that may be used to produce a wide
range of chemicals including 1, 4-butanediol, tetrahydrofurane, and γ-butyrolactone …