Plasmodium parasites responsible for the disease malaria reside within erythrocytes. Inside
this niche host cell, parasites internalize and digest host hemoglobin to source amino acids …

Plasmodium, the causative agent of malaria, is an obligate, intracellular, eukaryotic cell that
invades, replicates, and differentiates within hepatocytes and erythrocytes. Inside a host cell …

Development of malaria parasites within vertebrate erythrocytes requires nutrient uptake at
the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this …

Plasmodium falciparum parasites, the causative agents of malaria, modify their host
erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and …

Many variant proteins encoded by Plasmodium-specific multigene families are exported into
red blood cells (RBC). P. falciparum-specific variant proteins encoded by the var, stevor and …

Acquired antimalarial drug resistance produces treatment failures and has led to periods of
global disease resurgence. In Plasmodium falciparum, resistance is known to arise through …

Malaria parasites activate a broad-selectivity ion channel on their host erythrocyte
membrane to obtain essential nutrients from the bloodstream. This conserved channel …

Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated
nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact …

Malaria parasites increase erythrocyte permeability to diverse solutes including anions,
some cations, and organic solutes, as characterized with several independent methods …

Malaria parasites actively remodel the infected red blood cell (irbc) by exporting proteins into
the host cell cytoplasm. The human parasite Plasmodium falciparum exports particularly …