Combining scattering experiments and colloid theory to characterize charge effects in concentrated antibody solutions

A Gulotta, M Polimeni, S Lenton, CG Starr… - Molecular …, 2024 - ACS Publications
Charges and their contribution to protein–protein interactions are essential for the key
structural and dynamic properties of monoclonal antibody (mAb) solutions. In fact, they …

Sedimentation velocity FDS studies of antibodies in pooled human serum

JJ Correia, GR Bishop, PB Kyle, RT Wright… - European Biophysics …, 2023 - Springer
The biotech industry has great interest in investigating therapeutic proteins in high
concentration environments like human serum. The fluorescence detection system (Aviv …