The CRISPR system is a revolutionary genome editing tool that has the potential to
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …

CRISPR/Cas9 precision genome editing has revolutionized cancer treatment by introducing
specific alterations to the cancer genome. But the therapeutic potential of CRISPR/Cas9 is …

The pro-oncogenic activities of estrogen receptor alpha (ERα) drive breast cancer
pathogenesis. Endocrine therapies that impair the production of estrogen or the action of the …

Therapies that abrogate persistent androgen receptor (AR) signaling in castration-resistant
prostate cancer (CRPC) remain an unmet clinical need. The N-terminal domain of the AR …

Cancer cells are more vulnerable to abnormal redox fluctuations due to their imbalanced
antioxidant system, where cell surface receptors sense stress and trigger intracellular signal …

Repair of lesions in the plasma membrane is key to sustaining cellular homeostasis. Cells
maintain cytoplasmic as well as membrane-bound stores of repair proteins that can rapidly …

Androgens play an important role in prostate cancer development and progression.
Androgen action is mediated through the androgen receptor (AR), a ligand-dependent DNA …

Therapies that abrogate persistent androgen receptor (AR) signaling in castration resistant
prostate cancer (CRPC) remain an unmet clinical need. The N-terminal domain (NTD) of the …

The automated biological labs stand out because of the complexities and meanings in the
life science. The biological labs require a strict protocol of the experiment, and many …