Abstract β-Lactam, commonly referred as azetidin-2-one, is a multifunctional building block
for synthesizing β-amino ketones, γ-amino alcohols, and other compounds. Besides its well …

Histone deacetylase inhibitors (HDACIs) have a paramount importance in the acetylation
process of histone and non-histone proteins that are crucial players in the cellular epigenetic …

Herein, the synthesis and biological evaluation of 6-fluoro-3-(piperidin-4-yl) benzo [d]
isoxazole sulfonamide hybrids are discussed. All the synthesized molecules were assessed …

The (E)-N′-(substituted-benzylidene)-2-(7-fluoro-2-methoxyquinolin-8-yl) acetohydrazide-
hydrazone derivatives reported in this manuscript represent a new series of antibacterial …

We have synthesized a series of new β-lactam-azide derivatives as orally active anti-tumor
agents by targeting tubulin colchicine binding site and examined their structure activity …

Nitrogen–chlorine compounds and their derivatives are regarded as important heterocyclic
motifs, exhibiting a wide range of synthetic and pharmaceutical applications, such as N …

In this study, new bis‐1, 2, 3‐triazole derivatives, N, N′‐(1, 3‐phenylene) bis (2‐(4‐R‐1H‐
1, 2, 3‐triazol‐1‐yl) acetamide), were synthesized by copper‐catalyzed azide‐alkyne …

The elaboration of some N‐alkylated pyrazole‐tetrazole derivatives is reported. The
structures of the newly ones are verified using NMR and FTIR spectroscopies, mass …

The causes and progression of cancer are controlled by epigenetic processes. The
mechanisms involved in epigenetic regulation of cancer development, gene expression, and …

Cancer, accounts for around 10 million deaths annually, is the second leading cause of
death globally. The continuous emergency of drug-resistant cancers and the low specificity …