The development of controlled release systems for the regeneration of bone, cartilage, and
osteochondral interface is one of the hot topics in the field of tissue engineering and …

Utilization of living cells for therapies in regenerative medicine requires a fundamental
understanding of the interactions between different cells and their environment. Moreover …

The regenerative potential declines upon aging. This might be due to cell-intrinsic changes
in stem and progenitor cells or to influences by the microenvironment. Mesenchymal stem …

The importance of neurovascular crosstalk in development, normal physiology, and
pathologies is increasingly being recognized. Although vascular endothelial growth factor …

Identifying a reliable and effective cytokine or growth factor group has been the focus of stem
cell osteogenic induction studies. Concentrated growth factors (CGFs) as the novel …

Many studies have evaluated the biological effects of platelet rich plasma reporting the final
outcomes on cell and tissues. However, few studies have dealt with the kinetics of growth …

Objective: This study is focussed on the optimal method of autologous fibrinogen isolation
with regard to the yield and the use as a scaffold material. This is particularly relevant for …

Background: Platelet-rich fibrin (PRF) has gained popularity in craniofacial surgery, as it
provides an excellent reservoir of autologous growth factors (GFs) that are essential for bone …

Fabrication of three-dimensional (3D) fibrin scaffolds with tightly controllable pore sizes and
interconnections has been investigated. The scaffolds were produced using a combination …

Background: Application of platelet concentrates to wounds could speed healing. Leukocyte-
and platelet-rich fibrin, a relatively recent development, stands out from the other …