Promise and Perils of MicroRNA Discovery Research: Working Toward Quality Over Quantity
EK McIlwraith, W He, DD Belsham - Endocrinology, 2023 - academic.oup.com
Since the first microRNA (miRNA) was described in 1993 in the humble worm
Caenorhabditis elegans, the miRNA field has boomed, with more than 100 000 related …
Caenorhabditis elegans, the miRNA field has boomed, with more than 100 000 related …
Palmitate alters miRNA content of small extracellular vesicles secreted from NPY/AgRP-expressing hypothalamic neurons
EK McIlwraith, DD Belsham - Brain Research, 2023 - Elsevier
Exosomes (sEVs) are extracellular vesicles involved in the pathogenesis of obesity. Notably,
exosomal microRNAs (miRNAs) have emerged as crucial mediators of communication …
exosomal microRNAs (miRNAs) have emerged as crucial mediators of communication …
[HTML][HTML] The Involvement of the microRNAs miR-466c and miR-340 in the Palmitate-Mediated Dysregulation of Gonadotropin-Releasing Hormone Gene Expression
V Nkechika, N Zhang, DD Belsham - Genes, 2024 - mdpi.com
Diets high in saturated fatty acids are associated with obesity and infertility. Palmitate, the
most prevalent circulating saturated fatty acid, is sensed by hypothalamic neurons …
most prevalent circulating saturated fatty acid, is sensed by hypothalamic neurons …
[HTML][HTML] Bisphenol A Alters the Levels of miRNAs That Directly and/or Indirectly Target Neuropeptide Y in Murine Hypothalamic Neurons
KWY Mak, W He, N Loganathan, DD Belsham - Genes, 2023 - mdpi.com
The hypothalamus is a vital regulator of energy homeostasis. Orexigenic neuropeptide Y
(NPY) neurons within the hypothalamus can stimulate feeding and suppress energy …
(NPY) neurons within the hypothalamus can stimulate feeding and suppress energy …
[HTML][HTML] Immortalization and Characterization of GFAP-expressing Glial Cells from the Adult Mouse Hypothalamus, Cortex, and Brain Stem
N Loganathan, CV Lieu, DD Belsham - Neuroscience, 2024 - Elsevier
The generation of astrocyte cell lines from the hypothalamus is key to study glial involvement
in hypothalamic physiology, including energy homeostasis. As such, we immortalized …
in hypothalamic physiology, including energy homeostasis. As such, we immortalized …
Regulation of Neuropeptide Y by MicroRNAs in Hypothalamic Neuronal Cell Models
WYK Mak - 2023 - search.proquest.com
Orexigenic neuropeptide Y (NPY) neurons within the hypothalamus stimulate feeding
behaviour and suppress energy expenditure, and dysregulation to these neurons may …
behaviour and suppress energy expenditure, and dysregulation to these neurons may …