Zebrafish models of cardiac disease: From fortuitous mutants to precision medicine

JM González-Rosa - Circulation research, 2022 - Am Heart Assoc
Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …

The zebrafish (Danio rerio) as a model organism, with emphasis on applications for finfish aquaculture research

L Ribas, F Piferrer - Reviews in Aquaculture, 2014 - Wiley Online Library
The zebrafish (D anio rerio) is a freshwater teleost of the family C yprinidae that is
established as a model organism in many research fields. Here, we define the …

Advances in the study of heart development and disease using zebrafish

DR Brown, LA Samsa, L Qian, J Liu - Journal of cardiovascular …, 2016 - mdpi.com
Animal models of cardiovascular disease are key players in the translational medicine
pipeline used to define the conserved genetic and molecular basis of disease. Congenital …

[HTML][HTML] Zebrafish (Danio rerio) as a model for the study of aging and exercise: Physical ability and trainability decrease with age

MJH Gilbert, TC Zerulla, KB Tierney - Experimental gerontology, 2014 - Elsevier
A rapidly aging global population has motivated the development and use of models for
human aging. Studies on aging have shown parallels between zebrafish and humans at the …

Understanding fish muscle growth regulation to optimize aquaculture production

EJ Vélez, E Lutfi, S Azizi, M Perelló, C Salmerón… - Aquaculture, 2017 - Elsevier
Aquaculture has become an agronomic activity with noticeable development around the
world to respond to the simultaneous decrease of fish captures and the increasing demand …

Exercise intervention mitigates pathological liver changes in NAFLD zebrafish by activating SIRT1/AMPK/NRF2 signaling

Y Zou, Z Chen, C Sun, D Yang, Z Zhou, X Peng… - International Journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a common disease that causes serious liver
damage. Exercise is recognized as a non-pharmacological tool to improve the pathology of …

Increased mechanical loading through controlled swimming exercise induces bone formation and mineralization in adult zebrafish

S Suniaga, T Rolvien, A Vom Scheidt, IAK Fiedler… - Scientific Reports, 2018 - nature.com
Exercise promotes gain in bone mass through adaptive responses of the vertebrate
skeleton. This mechanism counteracts age-and disease-related skeletal degradation, but …

[HTML][HTML] The optimum velocity for Atlantic salmon post-smolts in RAS is a compromise between muscle growth and fish welfare

G Timmerhaus, CC Lazado, NAR Cabillon, BKM Reiten… - Aquaculture, 2021 - Elsevier
It is increasingly common to rear Atlantic salmon smolts for longer periods in recirculating
aquaculture systems (RAS) before transfer to sea cages. The conditions for this part of the …

Improving zebrafish laboratory welfare and scientific research through understanding their natural history

CJ Lee, GC Paull, CR Tyler - Biological Reviews, 2022 - Wiley Online Library
Globally, millions of zebrafish (Danio rerio) are used for scientific laboratory experiments for
which researchers have a duty of care, with legal obligations to consider their welfare …

Cardiovascular effects and molecular mechanisms of bisphenol A and its metabolite MBP in zebrafish

AR Brown, JM Green, J Moreman… - … science & technology, 2018 - ACS Publications
The plastic monomer bisphenol A (BPA) is one of the highest production volume chemicals
in the world and is frequently detected in wildlife and humans, particularly children. BPA has …