Biomarkers of sepsis: time for a reappraisal
Introduction Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic
functions. In a previous review, we identified 3370 references reporting on 178 different …
functions. In a previous review, we identified 3370 references reporting on 178 different …
New approaches to sepsis: molecular diagnostics and biomarkers
K Reinhart, M Bauer, NC Riedemann… - Clinical microbiology …, 2012 - Am Soc Microbiol
Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …
Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding
KN Iskander, MF Osuchowski… - Physiological …, 2013 - journals.physiology.org
Sepsis represents the host's systemic inflammatory response to a severe infection. It causes
substantial human morbidity resulting in hundreds of thousands of deaths each year …
substantial human morbidity resulting in hundreds of thousands of deaths each year …
The clinical challenge of sepsis identification and monitoring
JL Vincent - PLoS medicine, 2016 - journals.plos.org
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Graphene enabled low‐noise surface chemistry for multiplexed sepsis biomarker detection in whole blood
Affinity‐based electrochemical (EC) sensors offer a potentially valuable approach for point‐
of‐care (POC) diagnostics applications, and for the detection of diseases, such as sepsis …
of‐care (POC) diagnostics applications, and for the detection of diseases, such as sepsis …
The C-reactive protein/albumin ratio as an independent predictor of mortality in patients with severe sepsis or septic shock treated with early goal-directed therapy
Background Sepsis, including severe sepsis and septic shock, is a major cause of morbidity
and mortality. Albumin and C-reactive protein (CRP) are considered as good diagnostic …
and mortality. Albumin and C-reactive protein (CRP) are considered as good diagnostic …
Biomarkers in pneumonia—beyond procalcitonin
M Karakioulaki, D Stolz - International journal of molecular sciences, 2019 - mdpi.com
Pneumonia is the leading infectious cause of mortality worldwide and one of the most
common lower respiratory tract infections that is contributing significantly to the burden of …
common lower respiratory tract infections that is contributing significantly to the burden of …
Rapid diagnosis of sepsis
F Bloos, K Reinhart - Virulence, 2014 - Taylor & Francis
Fast and appropriate therapy is the cornerstone in the therapy of sepsis. However, the
discrimination of sepsis from non-infectious causes of inflammation may be difficult …
discrimination of sepsis from non-infectious causes of inflammation may be difficult …
C-reactive protein as a prognostic factor in intensive care admissions for sepsis: A Swedish multicenter study
H Koozi, M Lengquist, A Frigyesi - Journal of critical care, 2020 - Elsevier
Purpose C-reactive protein (CRP) is not included in the major intensive care unit (ICU)
prognostic tools such as the Simplified Acute Physiology Score (SAPS). We assessed CRP …
prognostic tools such as the Simplified Acute Physiology Score (SAPS). We assessed CRP …
Interpretation of C‐reactive protein concentrations in critically ill patients
C Lelubre, S Anselin… - BioMed research …, 2013 - Wiley Online Library
Infection is often difficult to recognize in critically ill patients because of the marked
coexisting inflammatory process. Lack of early recognition prevents timely resuscitation and …
coexisting inflammatory process. Lack of early recognition prevents timely resuscitation and …