A systematic review of rapid diagnostic tests for the detection of tuberculosis infection
Objectives To evaluate the effectiveness of available rapid diagnostic tests to identify
tuberculosis (TB) infection. Data sources Electronic databases were searched from 1975 to …
tuberculosis (TB) infection. Data sources Electronic databases were searched from 1975 to …
[HTML][HTML] Bacteriophage interactions with mammalian tissue: Therapeutic applications
The human body is a large reservoir for bacterial viruses known as bacteriophages
(phages), which participate in dynamic interactions with their bacterial and human hosts that …
(phages), which participate in dynamic interactions with their bacterial and human hosts that …
[HTML][HTML] The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from
resistance to infection to progressive disease. Here we report results from a forward genetic …
resistance to infection to progressive disease. Here we report results from a forward genetic …
Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features
GE Thwaites, TTH Chau, K Stepniewska, NH Phu… - The Lancet, 2002 - thelancet.com
Background The diagnosis of tuberculous meningitis is difficult. Discrimination of cases from
those of bacterial meningitis by clinical features alone is often impossible, and current …
those of bacterial meningitis by clinical features alone is often impossible, and current …
Diagnostic accuracy of nucleic acid amplification tests for tuberculous meningitis: a systematic review and meta-analysis
Conventional tests are not always helpful in making a diagnosis of tuberculous meningitis.
We did a systematic review and meta-analysis to establish the summary accuracy of nucleic …
We did a systematic review and meta-analysis to establish the summary accuracy of nucleic …
Indole propionic acid, an unusual antibiotic produced by the gut microbiota, with anti-inflammatory and antioxidant properties
Most antibiotics are produced by soil microbes and typically interfere with macromolecular
synthesis processes as their antibacterial mechanism of action. These natural products are …
synthesis processes as their antibacterial mechanism of action. These natural products are …
Tuberculous meningitis: pathogenesis, immune responses, diagnostic challenges, and the potential of biomarker-based approaches
Tuberculous meningitis (TBM) is the most devastating form of tuberculosis (TB), causing
high mortality or disability. Clinical management of the disease is challenging due to …
high mortality or disability. Clinical management of the disease is challenging due to …
Invasion of the central nervous system by intracellular bacteria
DA Drevets, PJM Leenen… - Clinical microbiology …, 2004 - Am Soc Microbiol
Infection of the central nervous system (CNS) is a severe and frequently fatal event during
the course of many diseases caused by microbes with predominantly intracellular life cycles …
the course of many diseases caused by microbes with predominantly intracellular life cycles …
Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study
VB Patel, G Theron, L Lenders, B Matinyena… - PLoS …, 2013 - journals.plos.org
Background Tuberculous meningitis (TBM) is difficult to diagnose promptly. The utility of the
Xpert MTB/RIF test for the diagnosis of TBM remains unclear, and the effect of host-and …
Xpert MTB/RIF test for the diagnosis of TBM remains unclear, and the effect of host-and …
The neurocritical care of tuberculous meningitis
Tuberculous meningitis is the most severe form of tuberculosis and often causes critical
illness with high mortality. Two primary management objectives are reducing intracranial …
illness with high mortality. Two primary management objectives are reducing intracranial …