Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …

With the reignited push for manned spaceflight and the development of companies focused
on commercializing spaceflight, increased human ventures into space are inevitable …

Humans are spending an increasing amount of time in space, where exposure to conditions
of microgravity causes 1–2% bone loss per month in astronauts. Through data collected …

Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

Research in microgravity is indispensable to disclose the impact of gravity on biological
processes and organisms. However, research in the near-Earth orbit is severely constrained …

Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation along the
osteogenic, chondrogenic, and adipogenic lineages and have potential applications in a …

Aging and a sedentary lifestyle conspire to reduce bone quantity and quality, decrease
muscle mass and strength, and undermine postural stability, culminating in an elevated risk …

For allogeneic cell therapies to reach their therapeutic potential, challenges related to
achieving scalable and robust manufacturing processes will need to be addressed. A …

The formation, maintenance, and repair of bone tissue involve close interlinks between two
stem cell types housed in the bone marrow: the hematologic stem cell originating …

Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …