Immune-mediated inflammatory diseases (IMIDs) are a spectrum of disorders of overlapping
immunopathogenesis, with a prevalence of up to 10% in Western populations and …

Gap junctions (GJ) and connexins play integral roles in cellular physiology and have been
found to be involved in multiple pathophysiological states from cancer to cardiovascular …

Acute myocarditis is an acute inflammatory cardiomyopathy associated with cardiac damage
triggered by a virus or a pathological immune activation. It may present with a wide range of …

Abstract Human Adenoviruses (HAdV) are nearly ubiquitous pathogens comprising
numerous sub-types that infect various tissues and organs. Among many encoded proteins …

BACKGROUND: Viral cardiac infection represents a significant clinical challenge
encompassing several etiological agents, disease stages, complex presentation, and a …

ABSTRACT β-coronaviruses cause acute infection in the upper respiratory tract, resulting in
various symptoms and clinical manifestations. OC43 is a human β-coronavirus that induces …

Macrophages are most important immune cell population in the heart. Cardiac macrophages
have broad-spectrum and heterogeneity, with two extreme polarization phenotypes: M1 pro …

Members of the CAR group of Ig‐like type I transmembrane proteins mediate homotypic cell
adhesion, share a common overall extracellular domain structure and are closely related at …

Connexins are essential for intercellular communication through gap junctions and the
maintenance of cellular and tissue homeostasis. Connexin 43 (Cx43) is the most …

The COVID-19 pandemic has paralyzed the global economy and resulted in millions of
deaths globally. People with co-morbidities like obesity, diabetes and hypertension are at an …