The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

[HTML][HTML] Role of glutathione in cancer: From mechanisms to therapies

L Kennedy, JK Sandhu, ME Harper, M Cuperlovic-Culf - Biomolecules, 2020 - mdpi.com
Glutathione (GSH) is the most abundant non-protein thiol present at millimolar
concentrations in mammalian tissues. As an important intracellular antioxidant, it acts as a …

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Advances and challenges in uncovering cold tolerance regulatory mechanisms in plants

Y Ding, Y Shi, S Yang - New Phytologist, 2019 - Wiley Online Library
Contents Summary I. Introduction II. Cold stress and physiological responses in plants III.
Sensing of cold signals in plants IV. Messenger molecules involved in cold signal …

[HTML][HTML] Molecular mechanisms that link oxidative stress, inflammation, and fibrosis in the liver

E Ramos-Tovar, P Muriel - Antioxidants, 2020 - mdpi.com
Activated hepatic stellate cells (HSCs) and myofibroblasts are the main producers of
extracellular matrix (ECM) proteins that form the fibrotic tissue that leads to hepatic fibrosis …

Mass spectrometry-based protein footprinting for higher-order structure analysis: fundamentals and applications

XR Liu, MM Zhang, ML Gross - Chemical reviews, 2020 - ACS Publications
Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …

[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

[HTML][HTML] Protein oxidation-formation mechanisms, detection and relevance as biomarkers in human diseases

R Kehm, T Baldensperger, J Raupbach, A Höhn - Redox Biology, 2021 - Elsevier
Generation of reactive oxygen species and related oxidants is an inevitable consequence of
life. Proteins are major targets for oxidation reactions, because of their rapid reaction rates …

[HTML][HTML] Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment

W Li, F Li, X Zhang, HK Lin, C Xu - Signal transduction and targeted …, 2021 - nature.com
More and more in-depth studies have revealed that the occurrence and development of
tumors depend on gene mutation and tumor heterogeneity. The most important …

[HTML][HTML] ROS/oxidative stress signaling in osteoarthritis

P Lepetsos, AG Papavassiliou - … et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Osteoarthritis is the most common joint disorder with increasing prevalence due to aging of
the population. Its multi-factorial etiology includes oxidative stress and the overproduction of …