Oxidative stress and resulting lipid peroxidation is involved in various and numerous
pathological states including inflammation, atherosclerosis, neurodegenerative diseases …

This review on recent research advances of the lipid peroxidation product 4-hydroxy-
nonenal (HNE) has four major topics: I. the formation of HNE in various organs and tissues …

A comprehensive focus on 4‐hydroxynonenal (HNE) as candidate molecule in a variety of
pathophysiological conditions occurring in humans is here provided. Despite an active, now …

Oxidative stress and lipid peroxidation (LPO) induced by inflammation, excess metal storage
and excess caloric intake cause generalized DNA damage, producing genotoxic and …

Multiple sclerosis (MS) exhibits many of the hallmarks of an inflammatory autoimmune
disorder including breakdown of the blood‐brain barrier (BBB), the recruitment of …

Aldehyde dehydrogenases (ALDHs) play a major role in the detoxification processes of
aldehydes generated in plants when exposed to abiotic stress. In previous studies, we have …

Reactive oxygen species (ROS) and subsequent oxidative damage may contribute to the
formation and persistence of multiple sclerosis (MS) lesions by acting on distinct …

4-Hydroxynonenal (HNE), a major lipid peroxidation product of n-6 polyunsaturated fatty
acids, which was discovered by the late Hermann Esterbauer, is a remarkable trifunctional …

hydroxynonenal (HNE) is a lipid hydroperoxide end product formed from the oxidation of n-6
polyunsaturated fatty acids. The relative abundance of HNE within the vasculature is …

Reactive oxygen species (ROS), a by-product of aerobic life, are highly reactive molecules
with unpaired electrons. The excess of ROS leads to oxidative stress, instigating the …