Validation of in-vitro bioassay methods: Application in herbal drug research
This present review described the validation method of in-vitro bioassay for its application in
herbal drug research. Seven sequencing steps that can be taken for performing a valid …
herbal drug research. Seven sequencing steps that can be taken for performing a valid …
In vitro cytotoxicity and cell viability assays: principles, advantages, and disadvantages
ÖS Aslantürk - Genotoxicity-A predictable risk to our actual world, 2018 - books.google.com
Cytotoxicity is one of the most important indicators for biological evaluation in vitro studies. In
vitro, chemicals such as drugs and pesticides have different cytotoxicity mechanisms such …
vitro, chemicals such as drugs and pesticides have different cytotoxicity mechanisms such …
[HTML][HTML] Screening for molecular glues–challenges and opportunities
GA Holdgate, C Bardelle, SK Berry, A Lanne… - SLAS Discovery, 2024 - Elsevier
Molecular glues are small molecules, typically smaller than PROTACs, and usually with
improved physicochemical properties that aim to stabilise the interaction between two …
improved physicochemical properties that aim to stabilise the interaction between two …
Nanofat cell aggregates: a nearly constitutive stromal cell inoculum for regenerative site-specific therapies
B Sesé, JM Sanmartín, B Ortega… - Plastic and …, 2019 - journals.lww.com
Background: Recent technology developed by Tulip Medical Products allows clinicians to
mechanically disaggregate fat tissue into small fat particles known as nanofat. The present …
mechanically disaggregate fat tissue into small fat particles known as nanofat. The present …
Streptomyces sp SM01 isolated from Indian soil produces a novel antibiotic picolinamycin effective against multi drug resistant bacterial strains
Abstract A Kashmir Himalayan (India) soil isolate, Streptomyces sp. SM01 was subjected to
small scale fermentation for the production of novel antimicrobials, picolinamycin (SM1). The …
small scale fermentation for the production of novel antimicrobials, picolinamycin (SM1). The …
Functionalized graphene oxide coating on Ti6Al4V alloy for improved biocompatibility and corrosion resistance
The present study focused on the development of magnesium-functionalized graphene
oxide (FGO) coating on titanium alloy (Ti6Al4V) by electrophoretic deposition. Graphene …
oxide (FGO) coating on titanium alloy (Ti6Al4V) by electrophoretic deposition. Graphene …
Neuroprotective role for RORA in Parkinson's disease revealed by analysis of post-mortem brain and a dopaminergic cell line
FS Al-Zaid, MJ Hurley, DT Dexter, GE Gillies - npj Parkinson's Disease, 2023 - nature.com
Parkinson's disease (PD) is almost twice as prevalent in men, which has largely been
attributed to neuroprotective effect of oestradiol in women. RORA (retinoic acid receptor …
attributed to neuroprotective effect of oestradiol in women. RORA (retinoic acid receptor …
Electronic cigarette refill fluids sold worldwide: flavor chemical composition, toxicity, and hazard analysis
EE Omaiye, W Luo, KJ McWhirter… - Chemical research in …, 2020 - ACS Publications
Flavor chemicals in electronic cigarette (EC) fluids, which may negatively impact human
health, have been studied in a limited number of countries/locations. To gain an …
health, have been studied in a limited number of countries/locations. To gain an …
Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling
C Yang, LP Slavetinska, M Fleuti… - Journal of the …, 2022 - ACS Publications
A new approach for synthesizing polycyclic heterofused 7-deazapurine heterocycles and the
corresponding nucleosides was developed based on C–H functionalization of diverse …
corresponding nucleosides was developed based on C–H functionalization of diverse …
Enhancing Ocular Drug Delivery: The Effect of Physicochemical Properties of Nanoparticles on the Mechanism of Their Uptake by Human Cornea Epithelial Cells
This study investigates the effect of nanoparticle size and surface chemistry on interactions
of the nanoparticles with human cornea epithelial cells (HCECs). Poly (lactic-co-glycolic) …
of the nanoparticles with human cornea epithelial cells (HCECs). Poly (lactic-co-glycolic) …