[HTML][HTML] Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions

M Aliabouzar, OD Kripfgans, JB Fowlkes… - … für Medizinische Physik, 2023 - Elsevier
The development of phase-shift droplets has broadened the scope of ultrasound-based
biomedical applications. When subjected to sufficient acoustic pressures, the …

Tumor-penetrating nanoplatform with ultrasound “unlocking” for cascade synergistic therapy and visual feedback under hypoxia

Z Xie, J Wang, Y Luo, B Qiao, W Jiang, L Zhu… - Journal of …, 2023 - Springer
Background Combined therapy based on the effects of cascade reactions of nanoplatforms
to combat specific solid tumor microenvironments is considered a cancer treatment strategy …

Acoustic droplet vaporization for on-demand modulation of microporosity in smart hydrogels

M Aliabouzar, C Quesada, ZQ Chan, JB Fowlkes… - Acta Biomaterialia, 2023 - Elsevier
Microporosity in hydrogels is critical for directing tissue formation and function. We have
developed a fibrin-based smart hydrogel, termed an acoustically responsive scaffold (ARS) …

[HTML][HTML] Ultra-high-speed dynamics of acoustic droplet vaporization in soft biomaterials: Effects of viscoelasticity, frequency, and bulk boiling point

BA Abeid, ML Fabiilli, JB Estrada… - Ultrasonics Sonochemistry, 2024 - Elsevier
Phase-shift droplets are a highly adaptable platform for biomedical applications of
ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound …

Acoustically responsive scaffolds: Unraveling release kinetics and mechanisms for sustained, steady drug delivery

H Xiao, M Aliabouzar, ML Fabiilli - Journal of Controlled Release, 2024 - Elsevier
Hydrogels can serve as local drug delivery depots that protect the biological activity of labile
therapeutics. However, drug release from conventional hydrogels is typically rapid, which is …

Real-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds

M Aliabouzar, BA Abeid, OD Kripfgans… - Applied Physics …, 2023 - pubs.aip.org
Phase-shift droplets provide a flexible and dynamic platform for therapeutic and diagnostic
applications of ultrasound. The spatiotemporal response of phase-shift droplets to focused …

[HTML][HTML] The radial dynamics and acoustic emissions of phase-shift droplets are impacted by mechanical properties of tissue-mimicking hydrogels

A Kaushik, BA Abeid, JB Estrada, JB Fowlkes… - Ultrasonics …, 2024 - Elsevier
Acoustic droplet vaporization (ADV) offers a dynamic approach for generating bubbles on
demand, presenting new possibilities in biomedical applications. Although ADV has been …

Acoustic super-resolved spatiotemporal monitoring of theranostic nanodroplets with tuned post-activation dynamics

A Huang, S An, Y Wang, K Feng, H Yu, Z Chen… - Applied Physics …, 2023 - pubs.aip.org
Phase-change nanodroplets (PCNDs) have been used as controllable theranostic agents in
diverse therapeutic and diagnostic scenarios over the years. However, there is still a …

Exploring the Post-activation Behavioral Patterns of Intratumorally-injected Theranostic Nanodroplets: An Ultrasound-only Extravascular Monitoring Technique

A Huang, Z Jia, H Wu, K Feng, C Zhang… - IEEE Transactions …, 2024 - ieeexplore.ieee.org
Phase-change nanodroplets (PCNDs) are customizable and controllable theranostic agents
of particular interest in extravascular therapies such as drug delivery and histotripsy. High …

A new sonoablation using acoustic droplet vaporization and focused ultrasound: A feasibility study

H Li, H He, J Tang, T Luo, G Yang, L Huang… - Medical …, 2023 - Wiley Online Library
Background Histotripsy and boiling histotripsy are two methods of mechanical ablation that
use high‐pressure focused ultrasound (FUS). Purpose Here, a new bubble sonoablation …