Vancomycin-resistant enterococci: a review of antimicrobial resistance mechanisms and perspectives of human and animal health
MO Ahmed, KE Baptiste - Microbial Drug Resistance, 2018 - liebertpub.com
Vancomycin-resistant enterococci (VRE) are both of medical and public health importance
associated with serious multidrug-resistant infections and persistent colonization …
associated with serious multidrug-resistant infections and persistent colonization …
The application of the CRISPR-Cas system in antibiotic resistance
S Tao, H Chen, N Li, W Liang - Infection and drug resistance, 2022 - Taylor & Francis
The emergence and global epidemic of antimicrobial resistance (AMR) poses a serious
threat to global public health in recent years. AMR genes are shared between bacterial …
threat to global public health in recent years. AMR genes are shared between bacterial …
Not all predicted CRISPR–Cas systems are equal: isolated cas genes and classes of CRISPR like elements
Abstract Background The CRISPR–Cas systems in prokaryotes are RNA-guided immune
systems that target and deactivate foreign nucleic acids. A typical CRISPR–Cas system …
systems that target and deactivate foreign nucleic acids. A typical CRISPR–Cas system …
CRISPR-Cas and restriction-modification act additively against conjugative antibiotic resistance plasmid transfer in Enterococcus faecalis
Enterococcus faecalis is an opportunistic pathogen and a leading cause of nosocomial
infections. Conjugative pheromone-responsive plasmids are narrow-host-range mobile …
infections. Conjugative pheromone-responsive plasmids are narrow-host-range mobile …
Let me upgrade you: impact of mobile genetic elements on enterococcal adaptation and evolution
Enterococci are Gram-positive bacteria that have evolved to thrive as both commensals and
pathogens, largely due to their accumulation of mobile genetic elements via horizontal gene …
pathogens, largely due to their accumulation of mobile genetic elements via horizontal gene …
Enterococcus faecalis CRISPR-Cas is a robust barrier to conjugative antibiotic resistance dissemination in the murine intestine
VJ Price, SW McBride, K Hullahalli, A Chatterjee… - Msphere, 2019 - Am Soc Microbiol
ABSTRACT CRISPR-Cas systems are barriers to horizontal gene transfer (HGT) in bacteria.
Little is known about CRISPR-Cas interactions with conjugative plasmids, and studies …
Little is known about CRISPR-Cas interactions with conjugative plasmids, and studies …
CRISPR-Cas system: the powerful modulator of accessory genomes in prokaryotes
Being frequently exposed to foreign nucleic acids, bacteria and archaea have developed an
ingenious adaptive defense system, called CRISPR-Cas. The system is composed of the …
ingenious adaptive defense system, called CRISPR-Cas. The system is composed of the …
An attenuated CRISPR-Cas system in Enterococcus faecalis permits DNA acquisition
K Hullahalli, M Rodrigues, UT Nguyen, K Palmer - MBio, 2018 - Am Soc Microbiol
Antibiotic-resistant bacteria are critical public health concerns. Among the prime causative
factors for the spread of antibiotic resistance is horizontal gene transfer (HGT). A useful …
factors for the spread of antibiotic resistance is horizontal gene transfer (HGT). A useful …
CRISPR-Cas inhibits plasmid transfer and immunizes bacteria against antibiotic resistance acquisition in manure
C Upreti, P Kumar, LM Durso… - Applied and …, 2024 - journals.asm.org
The horizontal transfer of antibiotic resistance genes among bacteria is a pressing global
issue. The bacterial defense system clustered regularly interspaced short palindromic …
issue. The bacterial defense system clustered regularly interspaced short palindromic …
CRISPR Arrays Away from cas Genes
CRISPR-Cas systems typically consist of a CRISPR array and cas genes that are organized
in one or more operons. However, a substantial fraction of CRISPR arrays are not adjacent …
in one or more operons. However, a substantial fraction of CRISPR arrays are not adjacent …