Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …

[HTML][HTML] Defining the genetic, genomic, cellular, and diagnostic architectures of psychiatric disorders

PF Sullivan, DH Geschwind - Cell, 2019 - cell.com
Studies of the genetics of psychiatric disorders have become one of the most exciting and
fast-moving areas in human genetics. A decade ago, there were few reproducible findings …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Genetics and epigenetics of autism spectrum disorder—current evidence in the field

B Wiśniowiecka-Kowalnik, BA Nowakowska - Journal of applied genetics, 2019 - Springer
Autism spectrum disorders (ASD) is a heterogenous group of neurodevelopmental disorders
characterized by problems in social interaction and communication as well as the presence …

Identification and evaluation of children with autism spectrum disorders

CP Johnson, SM Myers - Pediatrics, 2007 - publications.aap.org
Autism spectrum disorders are not rare; many primary care pediatricians care for several
children with autism spectrum disorders. Pediatricians play an important role in early …

Advances in autism genetics: on the threshold of a new neurobiology

BS Abrahams, DH Geschwind - Nature reviews genetics, 2008 - nature.com
Autism is a heterogeneous syndrome defined by impairments in three core domains: social
interaction, language and range of interests. Recent work has led to the identification of …

Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder

G Dawson - Development and psychopathology, 2008 - cambridge.org
Advances in the fields of cognitive and affective developmental neuroscience,
developmental psychopathology, neurobiology, genetics, and applied behavior analysis …

Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes

FX Castellanos, R Tannock - Nature Reviews Neuroscience, 2002 - nature.com
Research on attention-deficit/hyperactivity disorder (ADHD), a highly prevalent and
controversial condition, has, for the most part, been descriptive and atheoretical. The …

Lessons learned from studying syndromic autism spectrum disorders

Y Sztainberg, HY Zoghbi - Nature neuroscience, 2016 - nature.com
Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single …

Autism and pervasive developmental disorders

FR Volkmar, C Lord, A Bailey… - Journal of child …, 2004 - Wiley Online Library
The quantity and quality of research into autism and related conditions have increased
dramatically in recent years. Consequently we selectively review key accomplishments and …