Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Age-related macular degeneration (AMD) is a leading cause of blindness in aged
individuals. Recent advances have highlighted the essential role of immune processes in …

The mouse model of laser-induced choroidal neovascularization (CNV) has been used
extensively in studies of the exudative form of age-related macular degeneration (AMD) …

The treatment of brain tumors remains a challenge due to the limited accumulation of drugs
and nanoparticles. Here, we triggered the aggregation of gold nanoparticles (AuNPs) using …

Polymeric vehicles are versatile tools for therapeutic gene delivery. Many polymers—when
assembled with nucleic acids into vehicles—can protect the cargo from degradation and …

Subretinal fibrosis is a result of a wound healing response that follows choroidal
neovascularization in neovascular age-related macular degeneration (nAMD). Although anti …

Abstract Treatment and management of diseases of the posterior segment of the eye such
as diabetic retinopathy, retinoblastoma, retinitis pigmentosa, and choroidal …

Diabetes mellitus (DM) is a metabolic disease defined by elevated blood glucose (BG). DM
is a global epidemic and the prevalence is anticipated to continue to increase. The ocular …

Effective drug delivery to the retina still remains a challenge due to ocular elimination
mechanisms and complex barriers that selectively limit the entry of drugs into the eye. To …

Age‐related macular degeneration (AMD) disease has become a worldwide senile disease,
and frequent intravitreal injection of anti‐vascular endothelial growth factor (anti‐VEGF) is …