ALDH2 in alcoholic heart diseases: molecular mechanism and clinical implications

Y Zhang, J Ren - Pharmacology & therapeutics, 2011 - Elsevier
Alcoholic cardiomyopathy is manifested as cardiac hypertrophy, disrupted contractile
function and myofibrillary architecture. An ample amount of clinical and experimental …

Recent advances in understanding hypertension development in sub-Saharan Africa

AE Schutte, S Botha, CMT Fourie… - Journal of human …, 2017 - nature.com
Consistent reports indicate that hypertension is a particularly common finding in black
populations. Hypertension occurs at younger ages and is often more severe in terms of …

Revisiting the relationship between blood pressure and insulin-like growth factor-1

AE Schutte, M Volpe, G Tocci, E Conti - Hypertension, 2014 - Am Heart Assoc
Conflicting evidence exists on the relationship between blood pressure (BP) and insulin-like
growth factor-1 (IGF-1). We reviewed available articles and pooled extrapolated regression …

Relationship between objectively measured physical activity and subclinical cardiovascular disease: a systematic review

A Narendrula, E Brinza, CH Davey… - BMJ Open Sport & …, 2024 - bmjopensem.bmj.com
Introduction The association of physical activity (PA) with subclinical cardiovascular disease
(CVD) is unclear. Clarifying this relationship may inform cardiovascular prevention …

Exploring biomarkers associated with deteriorating vascular health using a targeted proteomics chip: The SABPA study

A Dieden, L Malan, CMC Mels, L Lammertyn… - Medicine, 2021 - journals.lww.com
Exploring biomarkers associated with deteriorating vascular... : Medicine Exploring biomarkers
associated with deteriorating vascular health using a targeted proteomics chip: The SABPA …

Determining cut-off values for neck circumference as a measure of the metabolic syndrome amongst a South African cohort: the SABPA study

S Hoebel, L Malan, JH De Ridder - Endocrine, 2012 - Springer
The aim was to determine receiver operating characteristic (ROC) neck circumference (NC)
cut offs best associated with the metabolic syndrome (MetS) in a South African cohort. We …

Self-reported alcohol intake is a better estimate of 5-year change in blood pressure than biochemical markers in low resource settings: the PURE study

MC Zatu, JM Van Rooyen, E Wentzel-Viljoen… - Journal of …, 2014 - journals.lww.com
Background: Despite criticism of self-reported alcohol intake, it is a valuable tool to screen
for alcohol abuse as a risk factor for cardiovascular disease. We aimed to compare various …

[HTML][HTML] Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study

M Hamer, R von Känel, M Reimann, NT Malan… - Atherosclerosis, 2015 - Elsevier
Recent work identified a high prevalence of modifiable risk factors for cardiovascular
disease (CVD) among urban black South Africans. The aim was to track the progression of …

Carotid intima‐media thickness but not carotid artery plaque in healthy individuals is linked to lean body mass

M Arnold, A Linden, R Clarke, Y Guo, H Du… - Journal of the …, 2019 - Am Heart Assoc
Background Lean body mass has been identified as a key determinant of left ventricular
mass and wall thickness. However, the importance of lean body mass or other body‐size …

A biomarker of tissue damage, lactate dehydrogenase, is associated with fibulin-1 and oxidative stress in blacks: the SAfrEIC study

GG Mokwatsi, AE Schutte, R Kruger - Biomarkers, 2016 - Taylor & Francis
Context: Extracellular matrix (ECM) remodeling and oxidative stress is present in
hypertension and associated arterial stiffness, but little is known on the physiological link …