State of the art advancements in sonodynamic therapy (SDT): Metal-Organic frameworks for SDT

Z Xiao, Q Chen, Y Yang, S Tu, B Wang, Y Qiu… - Chemical Engineering …, 2022 - Elsevier
Sonodynamic therapy (SDT) is a promising cancer therapy due to its noninvasiveness,
negligible side effects, and deep tissue penetration. However, the effect of SDT is …

[HTML][HTML] Mn-based MRI contrast agents: an overview

C Henoumont, M Devreux, S Laurent - Molecules, 2023 - mdpi.com
MRI contrast agents are required in the clinic to detect some pathologies, such as cancers.
Nevertheless, at the moment, only small extracellular and non-specific gadolinium …

Rational Design of Gd-DOTA-Type Contrast Agents for Hepatobiliary Magnetic Resonance Imaging

W Xu, Y Lu, J Xu, H Li, R Lan, R Gao… - Journal of Medicinal …, 2023 - ACS Publications
The safety risks of gadolinium (Gd3+)-based contrast agents (GBCAs) arise from their
inevitable leakage of Gd3+, and the pursuit of more stable GBCAs for magnetic resonance …

Nanoscale contrast agents for magnetic resonance imaging: A review

GJ Soufi, A Hekmatnia, S Iravani… - ACS Applied Nano …, 2022 - ACS Publications
Today, magnetic resonance imaging (MRI) is one of the most widely applied noninvasive
clinical imaging modalities with excellent applicability in bio-and nanomedicine, particularly …

Noninvasive Diagnosis of Kidney Dysfunction Using a Small-Molecule Manganese-Based Magnetic Resonance Imaging Probe

Y Zhang, K Xiang, J Pan, R Cheng, SK Sun - Analytical Chemistry, 2024 - ACS Publications
Contrast-enhanced magnetic resonance imaging (CE-MRI) is a promising approach for the
diagnosis of kidney diseases. However, safety concerns, including nephrogenic systemic …

Current advancement in the development of manganese complexes as magnetic resonance imaging probes

S Daksh, A Kaul, S Deep, A Datta - Journal of Inorganic Biochemistry, 2022 - Elsevier
Emerging non-invasive molecular imaging modalities can detect a pathophysiological state
at the molecular level before any anatomic changes are observed. Magnetic resonance …

Chiral Gd-DOTA as a Versatile Platform for Hepatobiliary and Tumor Targeting MRI Contrast Agents

W Xu, X Ye, M Wu, X Jiang, LH Hugo TSE… - Journal of Medicinal …, 2023 - ACS Publications
The leakage of gadolinium ions (Gd3+) from commercial Gd3+-based contrast agents
(GBCAs) in patients is currently the major safety concern in clinical magnetic resonance …

Lipophilic Group-Modified Manganese (II)-Based Contrast Agents for Vascular and Hepatobiliary Magnetic Resonance Imaging

Z Cai, L Jiang, Y Cao, S Fu, S Wang… - Journal of Medicinal …, 2024 - ACS Publications
Effective vascular and hepatic enhancement and better safety are the key drivers for
exploring gadolinium-free hepatobiliary contrast agents. Herein, a facile strategy proposes …

Research progress on manganese complexes as contrast agents for magnetic resonance imaging

F Wan, L Wu, X Chen, Y Zhang, L Jiang - Polyhedron, 2023 - Elsevier
Gadolinium (III)-based contrast agents (GBCAs) play a dominant role in contrast enhanced
magnetic resonance imaging (MRI) and are used to improve the accuracy of diagnoses. In …

Gadolinium-free magnetic resonance imaging of the liver via an oatp1-targeted manganese (III) porphyrin

NN Nyström, H Liu, FM Martinez… - Journal of Medicinal …, 2022 - ACS Publications
Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their
continued utility highly contentious, but the liver-specific GBCA Gd (III) ethoxybenzyl …