Epigenetic alterations in colorectal cancer: emerging biomarkers

Y Okugawa, WM Grady, A Goel - Gastroenterology, 2015 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …

[HTML][HTML] Molecular pathways involved in colorectal cancer: implications for disease behavior and prevention

D Colussi, G Brandi, F Bazzoli… - International journal of …, 2013 - mdpi.com
Research conducted during the past 30 years has increased our understanding of the
mechanisms involved in colorectal cancer initiation and development. The findings have …

[HTML][HTML] MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside

KKW To, CWS Tong, M Wu… - World journal of …, 2018 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that can post-
transcriptionally regulate the expression of various oncogenes and tumor suppressor genes …

[HTML][HTML] The pervasive role of the miR-181 family in development, neurodegeneration, and cancer

A Indrieri, S Carrella, P Carotenuto, S Banfi… - International journal of …, 2020 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …

ZEB 1‐associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat

S Meidhof, S Brabletz, W Lehmann… - EMBO molecular …, 2015 - embopress.org
Therapy resistance is a major clinical problem in cancer medicine and crucial for disease
relapse and progression. Therefore, the clinical need to overcome it, particularly for …

[HTML][HTML] Colorectal cancer disparity in African Americans: risk factors and carcinogenic mechanisms

GJ Augustus, NA Ellis - The American journal of pathology, 2018 - Elsevier
African Americans have the highest incidence and mortality rates of colorectal cancer (CRC)
of any ethnic group in the United States. Although some of these disparities can be …

Dissecting miRNA signature in colorectal cancer progression and metastasis

X Huang, X Zhu, Y Yu, W Zhu, L Jin, X Zhang, S Li… - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …

[HTML][HTML] Roles of microRNAs in ovarian cancer tumorigenesis: two decades later, what have we learned?

AA Alshamrani - Frontiers in oncology, 2020 - frontiersin.org
Ovarian cancer is one of the top gynecological malignancies that cause deaths among
females in the United States. At the molecular level, significant progress has been made in …

[HTML][HTML] Improving diagnosis, prognosis and prediction by using biomarkers in CRC patients

TK Nikolouzakis, L Vassilopoulou… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is among the most common cancers. In fact, it is placed in the third
place among the most diagnosed cancer in men, after lung and prostate cancer, and in the …

[HTML][HTML] Determination of 14 circulating microRNAs in Swedes and Iraqis with and without diabetes mellitus type 2

X Wang, J Sundquist, B Zöller, AA Memon, K Palmér… - PloS one, 2014 - journals.plos.org
Background Recent reports suggest that immigrants from Middle Eastern countries are a
high-risk group for type 2 diabetes (T2D) compared with Swedes, and that the pathogenesis …