It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a
crucial role in the entry of virus into the cell to cause the final infection. To investigate the …

Intracellular protein synthesis, folding, and degradation are tightly controlled processes to
ensure proper protein homeostasis. The proteasome is responsible for the degradation of …

Numerous studies have demonstrated an inverse link between cancer and Alzheimer's
disease (AD), with data suggesting that people with Alzheimer's have a decreased risk of …

Oral submucous fibrosis (OSF) is a chronic and insidious oral potentially malignant disorder
associated with a 4–17% risk of oral squamous cell carcinoma (OSCC). Our previous study …

Increasing evidence supports that proteasome activator subunit (PSME) genes play an
indispensable role in multiple tumors. The diverse expression patterns, prognostic value …

Background: The functional significance of the proteasome activator subunit (PSME) gene
family in the pathogenesis of skin cutaneous melanoma (SKCM) remains to be elucidated …

PA28γ is a nuclear activator of the 20S proteasome involved in the regulation of several
essential cellular processes, such as cell proliferation, apoptosis, nuclear dynamics, and …

Background Oral squamous cell carcinoma (OSCC) has the highest mortality rate among all
head and neck cancers and a relatively low five-year survival rate. Generally, the …

Introduction Oral Squamous Cell Carcinoma (OSCC), a common malignancy of the head
and neck region, is frequently diagnosed at advanced stages, necessitating the …

Abstract Interleukin 37 (IL-37) has been reported to play a significant role in innate immune
response and to be involved in several kinds of cancers. However, the investigation of …