Virus recognition of glycan receptors
Highlights•Most mammalian virus families use cell-surface glycans as receptors.•Glycan
receptors are diverse in structure and distribution, giving rise to species and tissue …
receptors are diverse in structure and distribution, giving rise to species and tissue …
Laminin-deficient muscular dystrophy: Molecular pathogenesis and structural repair strategies
PD Yurchenco, KK McKee, JR Reinhard, MA Rüegg - Matrix Biology, 2018 - Elsevier
Laminins are large heterotrimers composed of the α, β and γ subunits with distinct tissue-
specific and developmentally regulated expression patterns. The laminin-α2 subunit …
specific and developmentally regulated expression patterns. The laminin-α2 subunit …
Calcium binding by arabinogalactan polysaccharides is important for normal plant development
F Lopez-Hernandez, T Tryfona, A Rizza, XL Yu… - Plant Cell, 2020 - academic.oup.com
Arabinogalactan proteins (AGPs) are a family of plant extracellular proteoglycans involved in
many physiological events. AGPs are often anchored to the extracellular side of the plasma …
many physiological events. AGPs are often anchored to the extracellular side of the plasma …
Structural biology of laminins
E Hohenester - Essays in biochemistry, 2019 - portlandpress.com
Laminins are large cell-adhesive glycoproteins that are required for the formation and
function of basement membranes in all animals. Structural studies by electron microscopy in …
function of basement membranes in all animals. Structural studies by electron microscopy in …
Recent advancements in understanding mammalian O-mannosylation
The post-translational glycosylation of select proteins by O-linked mannose (O-mannose or
O-man) is a conserved modification from yeast to humans and has been shown to be …
O-man) is a conserved modification from yeast to humans and has been shown to be …
[HTML][HTML] Dystroglycanopathy: from elucidation of molecular and pathological mechanisms to development of treatment methods
M Kanagawa - International Journal of Molecular Sciences, 2021 - mdpi.com
Dystroglycanopathy is a collective term referring to muscular dystrophies with abnormal
glycosylation of dystroglycan. At least 18 causative genes of dystroglycanopathy have been …
glycosylation of dystroglycan. At least 18 causative genes of dystroglycanopathy have been …
What is the sugar code?
HJ Gabius, M Cudic, T Diercks, H Kaltner… - …, 2022 - Wiley Online Library
A code is defined by the nature of the symbols, which are used to generate information‐
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …
[HTML][HTML] Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice
MP Cataldi, P Lu, A Blaeser, QL Lu - Nature communications, 2018 - nature.com
O-mannosylated α-dystroglycan (α-DG) serves as receptors for cell–cell and cell–
extracellular matrix adhesion and signaling. Hypoglycosylation of α-DG is involved in cancer …
extracellular matrix adhesion and signaling. Hypoglycosylation of α-DG is involved in cancer …
TIM-1 mediates dystroglycan-independent entry of Lassa virus
RB Brouillette, EK Phillips, R Patel… - Journal of …, 2018 - Am Soc Microbiol
Lassa virus (LASV) is an Old World arenavirus responsible for hundreds of thousands of
infections in West Africa every year. LASV entry into a variety of cell types is mediated by …
infections in West Africa every year. LASV entry into a variety of cell types is mediated by …
The discovery of dystrophin, the protein product of the Duchenne muscular dystrophy gene
EP Hoffman - The FEBS journal, 2020 - Wiley Online Library
Duchenne muscular dystrophy was a well‐established medical and genetic enigma by the
1970s. Why was the new mutation rate so high in all world populations? Why were affected …
1970s. Why was the new mutation rate so high in all world populations? Why were affected …