Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of
drug development in the costly late stage, it has been widely recognized that drug ADMET …

There has been substantial attention in the expansion of new thiosemicarbazide derivatives
with diverse biological activities in recent years. Therefore, many scientists have prepared …

Curcumin (diferuloylmethane) is the main constituent extracted from turmeric. This
polyphenol is a non-toxic, potent compound with anticancer, anti-inflammatory, antibacterial …

In this 21 st century, Malaria remains a global burden and causes massive economic trouble
to disease-endemic nations. The control and eradication of malaria is a major challenge that …

In the current scenario of medicinal chemistry, quinoline plays a pivotal role in the design of
new heterocyclic compounds with several pharmacological properties, so the search for new …

The resistance of conventional antimalarial drugs against the malarial parasite continues to
pose a challenge to control the disease. The indiscriminate exploitation of the available …

In this study, a series of novel quinolinone-based thiosemicarbazones were designed in
silico and their activities tested in vitro against Mycobacterium tuberculosis (M. tuberculosis) …

Quinoline, a privileged scaffold in medicinal chemistry, has always been associated with a
multitude of biological activities. Especially in antimalarial and anticancer research …

Heterocyclic compounds containing the quinoline ring play a significant role in organic
synthesis and therapeutic chemistry. Polyfunctionalized quinolines have attracted the …

Nitrogen-doped graphene quantum dots (N-GQDs), which are less than 10 nm in size, are
an interesting member of the nanocarbon materials family. N-GQDs nanostructures have …