Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome
Dysregulation of protein synthesis is one of the key mechanisms underlying autism spectrum
disorder (ASD). However, the role of a major pathway controlling protein synthesis, the …
disorder (ASD). However, the role of a major pathway controlling protein synthesis, the …
Prenatal environmental stressors impair postnatal microglia function and adult behavior in males
CL Block, O Eroglu, SD Mague, CJ Smith, AM Ceasrine… - Cell reports, 2022 - cell.com
Gestational exposure to environmental toxins and socioeconomic stressors is
epidemiologically linked to neurodevelopmental disorders with strong male bias, such as …
epidemiologically linked to neurodevelopmental disorders with strong male bias, such as …
Commentary:'Camouflaging'in autistic people–reflection on Fombonne (2020)
Fombonne's (2020) editorial is a thought‐provoking appraisal of the literature on
'camouflaging', whereby some autistic people mask or compensate for their autistic …
'camouflaging', whereby some autistic people mask or compensate for their autistic …
An expanding manifold in transmodal regions characterizes adolescent reconfiguration of structural connectome organization
Adolescence is a critical time for the continued maturation of brain networks. Here, we
assessed structural connectome development in a large longitudinal sample ranging from …
assessed structural connectome development in a large longitudinal sample ranging from …
Preconfigured architecture of the developing mouse brain
In the adult brain, structural and functional parameters, such as synaptic sizes and neuronal
firing rates, follow right-skewed and heavy-tailed distributions. While this organization is …
firing rates, follow right-skewed and heavy-tailed distributions. While this organization is …
Time-resolved correlation of distributed brain activity tracks EI balance and accounts for diverse scale-free phenomena
Much of systems neuroscience posits the functional importance of brain activity patterns that
lack natural scales of sizes, durations, or frequencies. The field has developed prominent …
lack natural scales of sizes, durations, or frequencies. The field has developed prominent …
[HTML][HTML] Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment
The delicate balance between cortical excitation and inhibition (E/I) plays a pivotal role in
brain state changes. While previous studies have associated cortical hyperexcitability with …
brain state changes. While previous studies have associated cortical hyperexcitability with …