Toward a neurobiology of delusions
Delusions are the false and often incorrigible beliefs that can cause severe suffering in
mental illness. We cannot yet explain them in terms of underlying neurobiological …
mental illness. We cannot yet explain them in terms of underlying neurobiological …
Monitoring rapid chemical communication in the brain
DL Robinson, A Hermans, AT Seipel… - Chemical …, 2008 - ACS Publications
Neurotransmitters are chemicals that are secreted by neurons and relay messages to target
cells. The goal of in vivo electrochemistry is to provide a real-time view of neurotransmitters …
cells. The goal of in vivo electrochemistry is to provide a real-time view of neurotransmitters …
Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate
Coincident signaling by dopamine and glutamate is thought to be crucial for a variety of
motivated behaviors. Previous work has suggested that some midbrain dopamine neurons …
motivated behaviors. Previous work has suggested that some midbrain dopamine neurons …
Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement
JH Yoo, V Zell, N Gutierrez-Reed, J Wu… - Nature …, 2016 - nature.com
In addition to dopamine neurons, the ventral tegmental area (VTA) contains GABA-,
glutamate-and co-releasing neurons, and recent reports suggest a complex role for the …
glutamate-and co-releasing neurons, and recent reports suggest a complex role for the …
Mesocorticolimbic glutamatergic pathway
T Yamaguchi, HL Wang, X Li, TH Ng… - Journal of …, 2011 - Soc Neuroscience
The mesocorticolimbic dopamine (DA) system plays important roles in reward, motivation,
learning, memory, and movement. This system arises from the A10 region, comprising the …
learning, memory, and movement. This system arises from the A10 region, comprising the …
Reward system and addiction: what dopamine does and doesn't do
G Di Chiara, V Bassareo - Current opinion in pharmacology, 2007 - Elsevier
Addictive drugs share with palatable food the property of increasing extracellular dopamine
(DA), preferentially in the nucleus accumbens shell rather than in the core. However, by …
(DA), preferentially in the nucleus accumbens shell rather than in the core. However, by …
New medications for drug addiction hiding in glutamatergic neuroplasticity
PW Kalivas, ND Volkow - Molecular psychiatry, 2011 - nature.com
The repeated use of drugs that directly or indirectly stimulate dopamine transmission carry
addiction liability and produce enduring pathological changes in the brain circuitry that …
addiction liability and produce enduring pathological changes in the brain circuitry that …
Glutamatergic substrates of drug addiction and alcoholism
JT Gass, MF Olive - Biochemical pharmacology, 2008 - Elsevier
The past two decades have witnessed a dramatic accumulation of evidence indicating that
the excitatory amino acid glutamate plays an important role in drug addiction and …
the excitatory amino acid glutamate plays an important role in drug addiction and …
Neurotransmitter corelease: mechanism and physiological role
TS Hnasko, RH Edwards - Annual review of physiology, 2012 - annualreviews.org
Neurotransmitter identity is a defining feature of all neurons because it constrains the type of
information they convey, but many neurons release multiple transmitters. Although the …
information they convey, but many neurons release multiple transmitters. Although the …
Aberrant learning and memory in addiction
MM Torregrossa, PR Corlett, JR Taylor - Neurobiology of learning and …, 2011 - Elsevier
Over the past several years, drug addiction has increasingly been accepted to be a disease
of the brain as opposed to simply being due to a lack of willpower or personality flaw …
of the brain as opposed to simply being due to a lack of willpower or personality flaw …