Gastroesophageal reflux disease (GERD) is the most prevalent gastrointestinal disorder in
the United States, and leads to substantial morbidity, though associated mortality is rare. The …

The incidence of esophageal adenocarcinoma (EAC) has increased in many Western
countries and is higher in men than women. Some risk factors for EAC have been identified …

Objective To update the findings of the 2005 systematic review of population-based studies
assessing the epidemiology of gastro-oesophageal reflux disease (GERD). Design PubMed …

Despite guidelines for detection and treatment of Helicobacter pylori infection,
recommendations to test patients before and after therapy are commonly not followed in the …

Esophageal adenocarcinoma (EAC) is rapidly increasing in incidence in Western cultures.
Barrett's esophagus is the presumed precursor lesion for this cancer. Several other risk …

Gastric cancer is a prevalent yet heterogeneous disease. From diet and lifestyle to genetics
and ethnicity, our appreciation of the complexity of gastric cancer has evolved. This review …

A 29-year-old man presents with intermittent epigastric discomfort, without weight loss or
evidence of gastrointestinal bleeding. He reports no use of aspirin or nonsteroidal …

The incidence and mortality of gastric cancer have fallen dramatically in US and elsewhere
over the past several decades. Nonetheless, gastric cancer remains a major public health …

Helicobacter pylori (H. pylori) remains a prevalent, worldwide, chronic infection. Though the
prevalence of this infection appears to be decreasing in many parts of the world, H. pylori …

Background: The association of body mass index and gastroesophageal reflux disease
(GERD), including its complications (esophagitis, Barrett esophagus, and esophageal …