Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …

In the last decades, the understanding of the complex biological mechanisms that regulate
the life and growth of single cells and their reciprocal interaction has steadily increased. In …

Despite decades of research, how mammalian cell size is controlled remains unclear
because of the difficulty of directly measuring growth at the single-cell level. Here we report …

The size of a cell is determined by a combination of synthesis, self-assembly, incoming
matter and the balance of mechanical forces. Such processes operate at the single-cell …

We present a powerful and cost-effective method for active illumination using a digital
micromirror device (DMD) for quantitative phase-imaging techniques. Displaying binary …

High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …

We present cytometric classification of live healthy and cancerous cells by using the spatial
morphological and textural information found in the label‐free quantitative phase images of …

Viscoelasticity and its alteration in time and space has turned out to act as a key element in
fundamental biological processes in living systems, such as morphogenesis and motility …

The association of the intrinsic optical and biophysical properties of cells to homeostasis and
pathogenesis has long been acknowledged. Defining these label-free cellular features …

The multi-dimensional challenge of drug resistance is one of the pivotal hindrances for
cancer chemotherapy. A reductive approach to define and distinguish the main aspects of …