Understanding of cancer with the help of ever-expanding cutting edge technological tools
and bioinformatics is revolutionizing modern cancer research by broadening the space of …

The rates of melanoma and non‐melanoma skin cancer (NMSC) have been increasing over
the last twenty years in the United States, and this has been attributed to increased …

Abstract The KEAP1 (Kelch-like ECH-associated protein 1)-NRF2 (NF-E2-related factor 2)
system controls the biochemical defense activity against agents toxic to mammals and …

Transcription elongation rate influences cotranscriptional pre-mRNA maturation, but how
such kinetic coupling works is poorly understood. The formation of nonadenylated histone …

Super-enhancers (SEs) refer to large clusters of enhancers that drive gene expressions.
Recent data has provided novel insights in elucidating the roles of SEs in many diseases …

This review summarizes the carcinogenic mechanisms for 109 Group 1 human carcinogens
identified as causes of human cancer through Volume 106 of the IARC Monographs. The …

Simple Summary Connexins are proteins which comprise gap junctions in cells. These
junctions can directly connect neighboring cells and the cell interior with the extracellular …

Amphibian populations the world over are under threat of extinction, with as many as 40% of
assessed species listed as threatened under IUCN Red List criteria (a significantly higher …

The rapid transcriptional response to the transcription factor, glucocorticoid receptor (GR),
including gene activation or repression, is mediated by the spatial association of genes with …

It has long been widely acknowledged that ultraviolet (UV) light is an environment risk factor
that can lead to cancer, particularly skin cancer. However, it is worth noting that UV radiation …